| Game | Player Name | Prop | Line | Projection | Mean | Median | Over Count | Under Count | Robot Likes |
|---|---|---|---|---|---|---|---|---|---|
| Pittsburgh vs. Las Vegas | Maxx Crosby | Defense - Sacks | 0.25 | 0.80 | 0.75 | 1.00 | 6 | 4 | Over |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Receiving - Yards | 12.50 | 30.62 | 31.40 | 26.50 | 7 | 3 | Over |
| LA Chargers vs. Minnesota | Danielle Hunter | Defense - Sacks | 0.25 | 0.60 | 0.65 | 0.50 | 5 | 5 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Receiving - Yards | 8.50 | 19.20 | 29.75 | 16.00 | 6 | 2 | Over |
| New England vs. NY Jets | Dalvin Cook | Offense - Receiving - Yards | 7.50 | 15.60 | 18.50 | 13.00 | 7 | 3 | Over |
| New England vs. NY Jets | Dalvin Cook | Offense - Rushing - Yards | 26.50 | 53.91 | 53.90 | 51.00 | 9 | 1 | Over |
| Buffalo vs. Washington | Sam Howell | Offense - Passing - Interceptions | 0.50 | 1.00 | 1.00 | 1.00 | 2 | 0 | Over |
| Denver vs. Miami | Jaelan Phillips | Defense - Sacks | 0.25 | 0.50 | 0.50 | 0.50 | 7 | 3 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Fantasy Points - PrizePicks | 10.50 | 0.12 | 0.28 | 0.00 | 0 | 10 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing and Rushing Yards | 229.50 | 6.60 | 86.00 | 5.50 | 2 | 8 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing - Completions | 20.50 | 0.60 | 6.30 | 0.50 | 1 | 9 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing - Yards | 215.50 | 6.60 | 84.90 | 5.50 | 2 | 8 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Offense - Rushing - Yards | 24.50 | 48.17 | 47.30 | 46.00 | 9 | 1 | Over |
| Denver vs. Miami | Brandon Johnson | Offense - Receiving - Yards | 19.50 | 1.20 | 9.12 | 1.00 | 2 | 6 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Offense - Rushing and Receiving Yards | 60.50 | 3.77 | 4.80 | 0.00 | 0 | 10 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing - Attempts | 32.50 | 2.40 | 11.10 | 2.00 | 2 | 8 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Offense - Rushing - Yards | 45.50 | 3.73 | 4.80 | 0.00 | 0 | 10 | Under |
| New England vs. NY Jets | Dalvin Cook | Offense - Rushing and Receiving Yards | 38.50 | 73.79 | 72.40 | 64.50 | 8 | 2 | Over |
| Dallas vs. Arizona | Rondale Moore | Offense - Receiving - Yards | 24.50 | 46.88 | 47.90 | 41.00 | 8 | 2 | Over |
| Chicago vs. Kansas City | Jerick McKinnon | Offense - Receiving - Yards | 13.50 | 25.80 | 32.70 | 21.50 | 6 | 4 | Over |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Receiving - Yards | 14.50 | 1.39 | 1.20 | 0.00 | 0 | 10 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Offense - Rushing - Attempts | 12.50 | 1.32 | 2.30 | 0.00 | 1 | 9 | Under |
| Indianapolis vs. Baltimore | Zack Moss | Fantasy Points - PrizePicks | 11.50 | 1.50 | 4.70 | 1.25 | 1 | 9 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Fantasy Points - PrizePicks | 13.00 | 1.80 | 4.90 | 1.50 | 1 | 9 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Rushing - Yards | 10.50 | 1.49 | 1.10 | 0.00 | 0 | 10 | Under |
| Dallas vs. Arizona | Rico Dowdle | Offense - Rushing - Yards | 27.50 | 4.41 | 4.00 | 0.00 | 0 | 6 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Rushing - Yards | 3.50 | 0.60 | 5.50 | 0.50 | 3 | 7 | Under |
| New Orleans vs. Green Bay | Jordan Love | Fantasy Points - PrizePicks | 14.50 | 2.56 | 5.81 | 2.13 | 1 | 9 | Under |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Receiving - Receptions | 2.50 | 0.45 | 0.40 | 0.00 | 1 | 9 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Receiving - Yards | 15.50 | 2.81 | 3.70 | 3.00 | 0 | 10 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Rushing and Receiving Yards | 56.50 | 102.00 | 103.50 | 85.00 | 8 | 0 | Over |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Rushing and Receiving Yards | 71.50 | 15.00 | 39.00 | 12.50 | 3 | 7 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Rushing and Receiving Yards | 70.50 | 16.80 | 20.50 | 14.00 | 0 | 10 | Under |
| New Orleans vs. Green Bay | Jordan Love | Offense - Passing - Yards | 211.50 | 50.40 | 78.30 | 42.00 | 1 | 9 | Under |
| Chicago vs. Kansas City | Darnell Mooney | Offense - Receiving - Yards | 29.50 | 51.86 | 51.90 | 53.00 | 8 | 2 | Over |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Rushing - Attempts | 14.50 | 3.60 | 8.00 | 3.00 | 3 | 7 | Under |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Rushing - Yards | 54.50 | 15.00 | 37.80 | 12.50 | 4 | 6 | Under |
| New England vs. NY Jets | Mac Jones | Offense - Rushing - Yards | 8.50 | 2.40 | 3.70 | 2.00 | 2 | 8 | Under |
| Atlanta vs. Detroit | Tyler Allgeier | Offense - Rushing - Yards | 46.50 | 79.60 | 78.60 | 74.50 | 9 | 1 | Over |
| Buffalo vs. Washington | Sam Howell | Offense - Rushing - Yards | 12.50 | 21.40 | 23.00 | 23.00 | 1 | 1 | Over |
| Dallas vs. Arizona | Micah Parsons | Defense - Sacks | 1.00 | 0.30 | 0.55 | 0.25 | 1 | 9 | Under |
| Buffalo vs. Washington | Leonard Floyd | Defense - Sacks | 0.50 | 0.85 | 0.85 | 1.00 | 6 | 4 | Over |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Rushing - Yards | 49.50 | 15.00 | 16.80 | 12.50 | 1 | 9 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Rushing - Attempts | 11.50 | 3.60 | 4.50 | 3.00 | 0 | 10 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Receiving - Receptions | 2.50 | 0.80 | 0.90 | 1.00 | 1 | 9 | Under |
| Chicago vs. Kansas City | Darnell Mooney | Offense - Receiving - Receptions | 2.50 | 4.16 | 4.00 | 4.00 | 8 | 2 | Over |
| Indianapolis vs. Baltimore | Gardner Minshew | Fantasy Points - PrizePicks | 14.50 | 4.87 | 3.96 | 0.00 | 1 | 9 | Under |
| LA Chargers vs. Minnesota | Joshua Kelley | Fantasy Points - PrizePicks | 13.00 | 4.38 | 5.07 | 3.65 | 1 | 9 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Rushing - Yards | 3.50 | 1.20 | 4.30 | 1.00 | 4 | 6 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Receiving - Yards | 15.50 | 5.40 | 6.40 | 4.50 | 2 | 8 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Offense - Rushing and Receiving Yards | 34.50 | 56.79 | 55.80 | 52.00 | 8 | 2 | Over |
| Denver vs. Miami | Durham Smythe | Offense - Receiving - Yards | 27.50 | 10.20 | 14.30 | 8.50 | 2 | 8 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Rushing - Yards | 44.50 | 72.46 | 73.75 | 69.00 | 6 | 2 | Over |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Receiving - Yards | 14.50 | 5.59 | 5.30 | 6.00 | 1 | 9 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Interceptions | 0.50 | 0.80 | 0.80 | 1.00 | 6 | 4 | Over |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Interceptions | 0.50 | 0.80 | 1.00 | 1.00 | 6 | 4 | Over |
| New England vs. NY Jets | Allen Lazard | Offense - Receiving - Yards | 30.50 | 48.76 | 49.40 | 51.50 | 8 | 2 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Rushing - Yards | 58.50 | 93.44 | 92.00 | 83.50 | 9 | 1 | Over |
| Atlanta vs. Detroit | Josh Reynolds | Offense - Receiving - Yards | 42.50 | 18.00 | 22.40 | 15.00 | 2 | 8 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Rushing - Yards | 12.50 | 5.33 | 6.00 | 5.00 | 1 | 9 | Under |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Rushing and Receiving Yards | 78.50 | 35.07 | 34.70 | 30.50 | 1 | 9 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Fantasy Points - PrizePicks | 6.50 | 10.10 | 9.88 | 11.15 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Receiving - Yards | 15.50 | 24.00 | 25.10 | 20.00 | 6 | 4 | Over |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Rushing - Attempts | 15.50 | 7.06 | 6.90 | 7.00 | 1 | 9 | Under |
| Dallas vs. Arizona | Jake Ferguson | Offense - Receiving - Yards | 23.50 | 10.80 | 15.10 | 9.00 | 3 | 7 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Receiving - Receptions | 1.50 | 2.31 | 2.50 | 2.00 | 5 | 3 | Over |
| Tennessee vs. Cleveland | Donovan Peoples-Jones | Offense - Receiving - Yards | 28.50 | 43.80 | 43.40 | 36.50 | 6 | 4 | Over |
| Dallas vs. Arizona | Jake Ferguson | Offense - Receiving - Receptions | 2.50 | 1.20 | 1.30 | 1.00 | 1 | 9 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Receiving - Receptions | 2.50 | 1.20 | 1.30 | 1.00 | 2 | 8 | Under |
| LA Chargers vs. Minnesota | Josh Palmer | Offense - Receiving - Receptions | 2.50 | 3.80 | 3.80 | 4.00 | 6 | 4 | Over |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Interceptions | 0.50 | 0.24 | 0.50 | 0.00 | 3 | 7 | Under |
| Denver vs. Miami | Raheem Mostert | Offense - Receiving - Yards | 13.50 | 6.60 | 12.10 | 5.50 | 3 | 7 | Under |
| Houston vs. Jacksonville | Dameon Pierce | Offense - Rushing - Yards | 43.50 | 65.64 | 66.40 | 75.50 | 6 | 4 | Over |
| Denver vs. Miami | Jerry Jeudy | Offense - Receiving - Yards | 49.50 | 74.64 | 73.60 | 69.00 | 8 | 2 | Over |
| New England vs. NY Jets | Breece Hall | Fantasy Points - PrizePicks | 9.50 | 14.32 | 15.10 | 14.00 | 7 | 1 | Over |
| LA Chargers vs. Minnesota | Josh Palmer | Offense - Receiving - Yards | 27.50 | 41.40 | 41.40 | 44.00 | 7 | 3 | Over |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Rushing - Yards | 58.50 | 29.18 | 29.40 | 26.50 | 1 | 9 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing - Yards | 224.50 | 112.10 | 113.40 | 126.50 | 2 | 8 | Under |
| Pittsburgh vs. Las Vegas | Austin Hooper | Offense - Receiving - Yards | 20.50 | 30.73 | 31.40 | 31.50 | 7 | 3 | Over |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Touchdowns | 1.50 | 2.24 | 2.00 | 2.00 | 6 | 4 | Over |
| Indianapolis vs. Baltimore | Gus Edwards | Fantasy Points - PrizePicks | 9.50 | 4.87 | 5.16 | 5.60 | 1 | 9 | Under |
| Buffalo vs. Washington | James Cook | Offense - Receiving - Yards | 17.50 | 9.00 | 10.10 | 7.50 | 1 | 9 | Under |
| Philadelphia vs. Tampa Bay | Cade Otton | Fantasy Points - PrizePicks | 6.50 | 3.36 | 4.07 | 2.80 | 2 | 8 | Under |
| Buffalo vs. Washington | Dawson Knox | Offense - Receiving - Yards | 25.50 | 37.80 | 38.70 | 31.50 | 5 | 5 | Over |
| Indianapolis vs. Baltimore | Lamar Jackson | Fantasy Points - PrizePicks | 20.50 | 10.62 | 9.85 | 9.13 | 2 | 8 | Under |
| Chicago vs. Kansas City | Cole Kmet | Offense - Receiving - Yards | 28.50 | 42.01 | 42.90 | 38.00 | 6 | 4 | Over |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing - Attempts | 29.50 | 15.56 | 16.70 | 19.00 | 3 | 7 | Under |
| LA Rams vs. Cincinnati | Matthew Stafford | Offense - Passing - Touchdowns | 1.50 | 0.80 | 1.00 | 1.00 | 2 | 8 | Under |
| Indianapolis vs. Baltimore | Mark Andrews | Fantasy Points - PrizePicks | 12.50 | 6.70 | 6.85 | 6.70 | 1 | 9 | Under |
| LA Rams vs. Cincinnati | Tutu Atwell | Offense - Receiving - Yards | 55.50 | 30.00 | 36.30 | 25.00 | 2 | 8 | Under |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Receiving - Receptions | 1.50 | 0.83 | 0.70 | 0.00 | 2 | 8 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing and Rushing Yards | 278.50 | 154.40 | 148.50 | 193.00 | 2 | 8 | Under |
| New England vs. NY Jets | Randall Cobb | Offense - Receiving - Yards | 12.50 | 18.00 | 26.70 | 15.00 | 5 | 5 | Over |
| Tennessee vs. Cleveland | Elijah Moore | Offense - Receiving - Yards | 37.50 | 21.00 | 28.60 | 17.50 | 4 | 6 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing - Completions | 19.50 | 10.96 | 10.80 | 10.50 | 2 | 8 | Under |
| New England vs. NY Jets | Garrett Wilson | Offense - Receiving - Yards | 48.50 | 69.73 | 70.80 | 83.50 | 6 | 4 | Over |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Touchdowns | 1.50 | 2.14 | 1.90 | 2.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Rushing - Yards | 48.50 | 69.01 | 70.40 | 83.00 | 7 | 3 | Over |
| New England vs. NY Jets | Zach Wilson | Offense - Rushing - Yards | 13.50 | 7.80 | 10.80 | 6.50 | 4 | 6 | Under |
| Denver vs. Miami | Jerry Jeudy | Offense - Receiving - Receptions | 4.00 | 5.67 | 5.30 | 6.00 | 7 | 3 | Over |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Rushing - Yards | 17.50 | 10.20 | 18.10 | 8.50 | 4 | 6 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Rushing - Attempts | 2.50 | 3.51 | 3.50 | 4.00 | 7 | 3 | Over |
| Chicago vs. Kansas City | Justin Fields | Fantasy Points - PrizePicks | 18.00 | 25.26 | 24.46 | 23.60 | 7 | 3 | Over |
| Denver vs. Miami | Jason Sanders | Special Teams - Field Goals Made | 1.50 | 2.10 | 2.10 | 2.50 | 7 | 3 | Over |
| Carolina vs. Seattle | Andy Dalton | Offense - Passing - Interceptions | 0.50 | 0.69 | 0.50 | 0.00 | 4 | 6 | Over |
| Philadelphia vs. Tampa Bay | Chris Godwin | Offense - Receiving - Yards | 53.50 | 74.23 | 75.50 | 67.00 | 9 | 1 | Over |
| Tennessee vs. Cleveland | Amari Cooper | Fantasy Points - PrizePicks | 13.50 | 8.34 | 10.94 | 6.95 | 2 | 8 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Receiving - Receptions | 3.50 | 4.80 | 4.30 | 4.00 | 5 | 5 | Over |
| Buffalo vs. Washington | James Cook | Fantasy Points - PrizePicks | 11.50 | 7.26 | 8.07 | 8.45 | 2 | 8 | Under |
| New Orleans vs. Green Bay | Jordan Love | Offense - Passing - Interceptions | 0.50 | 0.32 | 0.30 | 0.00 | 2 | 8 | Under |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Fantasy Points - PrizePicks | 9.50 | 6.06 | 6.25 | 5.05 | 2 | 8 | Under |
| Chicago vs. Kansas City | D.J. Moore | Offense - Receiving - Yards | 44.50 | 60.60 | 61.50 | 51.00 | 5 | 5 | Over |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Fantasy Points - PrizePicks | 14.50 | 9.29 | 10.24 | 7.74 | 2 | 8 | Under |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Rushing - Yards | 71.50 | 96.80 | 95.80 | 85.50 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Rushing - Attempts | 12.50 | 16.89 | 17.00 | 18.50 | 7 | 3 | Over |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Rushing and Receiving Yards | 90.50 | 122.13 | 120.90 | 108.00 | 7 | 3 | Over |
| Denver vs. Miami | Samaje Perine | Offense - Rushing - Yards | 20.50 | 27.60 | 33.00 | 23.00 | 7 | 3 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Rushing - Attempts | 9.50 | 12.73 | 11.50 | 11.50 | 6 | 4 | Over |
| Houston vs. Jacksonville | Travis Etienne | Fantasy Points - PrizePicks | 14.50 | 9.61 | 8.80 | 8.90 | 2 | 8 | Under |
| Dallas vs. Arizona | Zach Ertz | Offense - Receiving - Yards | 30.50 | 40.67 | 41.30 | 42.50 | 7 | 3 | Over |
| New Orleans vs. Green Bay | Anders Carlson | Special Teams - Field Goals Made | 1.50 | 1.00 | 1.00 | 1.00 | 0 | 1 | Under |
| Dallas vs. Arizona | Brandon Aubrey | Special Teams - Field Goals Made | 1.50 | 2.00 | 2.00 | 2.00 | 1 | 0 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Rushing - Yards | 4.50 | 3.00 | 7.40 | 2.50 | 5 | 5 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Rushing - Yards | 12.50 | 16.64 | 18.00 | 14.00 | 6 | 4 | Over |
| Chicago vs. Kansas City | Cole Kmet | Fantasy Points - PrizePicks | 7.50 | 9.96 | 10.03 | 8.30 | 5 | 5 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Fantasy Points - PrizePicks | 10.50 | 13.89 | 13.22 | 12.25 | 6 | 4 | Over |
| Houston vs. Jacksonville | Dameon Pierce | Offense - Rushing and Receiving Yards | 60.50 | 79.67 | 79.50 | 86.50 | 6 | 4 | Over |
| New England vs. NY Jets | Garrett Wilson | Offense - Receiving - Receptions | 4.00 | 5.26 | 5.40 | 5.00 | 6 | 4 | Over |
| Atlanta vs. Detroit | Mack Hollins | Offense - Receiving - Receptions | 2.50 | 3.29 | 3.20 | 3.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Rushing - Attempts | 17.50 | 22.95 | 22.10 | 21.50 | 7 | 3 | Over |
| New England vs. NY Jets | Hunter Henry | Offense - Receiving - Yards | 29.50 | 38.64 | 37.50 | 46.00 | 6 | 4 | Over |
| Dallas vs. Arizona | James Conner | Offense - Rushing - Yards | 54.50 | 70.90 | 69.90 | 66.00 | 8 | 2 | Over |
| New Orleans vs. Green Bay | Chris Olave | Fantasy Points - PrizePicks | 14.00 | 9.82 | 9.99 | 8.60 | 2 | 8 | Under |
| Indianapolis vs. Baltimore | Alec Pierce | Offense - Receiving - Yards | 32.50 | 22.80 | 22.50 | 19.00 | 2 | 8 | Under |
| Denver vs. Miami | Raheem Mostert | Fantasy Points - PrizePicks | 13.50 | 9.48 | 9.86 | 7.90 | 3 | 7 | Under |
| Denver vs. Miami | Javonte Williams | Offense - Receiving - Yards | 14.50 | 10.20 | 12.80 | 8.50 | 2 | 8 | Under |
| Buffalo vs. Washington | James Cook | Offense - Rushing and Receiving Yards | 74.50 | 52.99 | 53.70 | 45.00 | 3 | 7 | Under |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Rushing and Receiving Yards | 89.50 | 115.25 | 116.00 | 122.50 | 8 | 2 | Over |
| New England vs. NY Jets | DeVante Parker | Fantasy Points - PrizePicks | 8.50 | 6.08 | 6.79 | 5.85 | 3 | 7 | Under |
| Dallas vs. Arizona | Zach Ertz | Offense - Receiving - Receptions | 4.00 | 5.14 | 5.10 | 6.00 | 7 | 3 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Rushing and Receiving Yards | 64.50 | 82.77 | 82.30 | 91.00 | 7 | 3 | Over |
| Philadelphia vs. Tampa Bay | Rachaad White | Fantasy Points - PrizePicks | 13.00 | 9.32 | 9.05 | 8.95 | 3 | 7 | Under |
| Atlanta vs. Detroit | Desmond Ridder | Fantasy Points - PrizePicks | 14.00 | 10.08 | 9.42 | 8.40 | 1 | 4 | Under |
| Carolina vs. Seattle | Adam Thielen | Fantasy Points - PrizePicks | 8.50 | 6.12 | 7.15 | 5.10 | 3 | 7 | Under |
| LA Chargers vs. Minnesota | T.J. Hockenson | Fantasy Points - PrizePicks | 13.50 | 9.72 | 10.58 | 8.10 | 2 | 8 | Under |
| Denver vs. Miami | Samaje Perine | Offense - Rushing and Receiving Yards | 41.50 | 30.00 | 51.10 | 25.00 | 4 | 6 | Under |
| Buffalo vs. Washington | Terry McLaurin | Offense - Receiving - Yards | 51.50 | 65.50 | 66.90 | 63.00 | 7 | 3 | Over |
| LA Chargers vs. Minnesota | Cameron Dicker | Special Teams - Field Goals Made | 1.50 | 1.90 | 1.90 | 2.00 | 7 | 3 | Over |
| Atlanta vs. Detroit | Riley Patterson | Special Teams - Field Goals Made | 1.50 | 1.90 | 1.90 | 2.00 | 7 | 3 | Over |
| Atlanta vs. Detroit | Younghoe Koo | Special Teams - Field Goals Made | 1.50 | 1.90 | 1.90 | 2.00 | 6 | 4 | Over |
| Carolina vs. Seattle | Jason Myers | Special Teams - Field Goals Made | 1.50 | 1.90 | 1.90 | 2.00 | 6 | 4 | Over |
| Tennessee vs. Cleveland | Myles Garrett | Defense - Sacks | 0.75 | 0.95 | 0.95 | 1.00 | 7 | 3 | Over |
| LA Chargers vs. Minnesota | Justin Jefferson | Fantasy Points - PrizePicks | 21.00 | 15.44 | 15.76 | 17.30 | 4 | 6 | Under |
| Houston vs. Jacksonville | Christian Kirk | Fantasy Points - PrizePicks | 12.50 | 9.22 | 10.05 | 9.60 | 4 | 6 | Under |
| Houston vs. Jacksonville | Nico Collins | Fantasy Points - PrizePicks | 12.00 | 8.90 | 8.60 | 8.15 | 1 | 9 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Rushing - Yards | 48.50 | 36.00 | 35.10 | 34.50 | 3 | 7 | Under |
| Houston vs. Jacksonville | Dalton Schultz | Offense - Receiving - Yards | 31.50 | 39.60 | 42.40 | 33.00 | 6 | 4 | Over |
| Denver vs. Miami | Courtland Sutton | Fantasy Points - PrizePicks | 10.00 | 7.43 | 7.35 | 9.25 | 4 | 6 | Under |
| Dallas vs. Arizona | Brandin Cooks | Offense - Receiving - Yards | 39.50 | 49.64 | 50.60 | 42.50 | 5 | 5 | Over |
| New England vs. NY Jets | Tyler Conklin | Offense - Receiving - Yards | 22.50 | 16.80 | 24.50 | 14.00 | 4 | 6 | Under |
| New England vs. NY Jets | Zach Wilson | Offense - Passing - Completions | 17.50 | 13.11 | 14.60 | 15.00 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing and Rushing Yards | 244.50 | 183.60 | 184.60 | 190.50 | 0 | 10 | Under |
| Philadelphia vs. Tampa Bay | DeVonta Smith | Offense - Receiving - Yards | 61.50 | 76.68 | 78.10 | 65.50 | 6 | 4 | Over |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Rushing - Yards | 34.50 | 42.91 | 44.10 | 40.50 | 5 | 5 | Over |
| New England vs. NY Jets | Michael Carter | Offense - Rushing - Yards | 8.50 | 6.43 | 6.50 | 5.50 | 2 | 8 | Under |
| Dallas vs. Arizona | James Conner | Offense - Receiving - Yards | 16.50 | 20.49 | 21.30 | 19.50 | 7 | 3 | Over |
| Philadelphia vs. Tampa Bay | Mike Evans | Fantasy Points - PrizePicks | 12.50 | 9.48 | 11.97 | 7.90 | 2 | 8 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Rushing - Yards | 12.50 | 15.49 | 16.70 | 18.00 | 6 | 4 | Over |
| Philadelphia vs. Tampa Bay | Mike Evans | Offense - Receiving - Yards | 54.50 | 67.37 | 68.70 | 56.50 | 5 | 5 | Over |
| Dallas vs. Arizona | CeeDee Lamb | Offense - Receiving - Yards | 69.50 | 85.72 | 87.00 | 88.50 | 7 | 3 | Over |
| Dallas vs. Arizona | Tony Pollard | Offense - Rushing - Yards | 72.50 | 55.90 | 55.50 | 65.00 | 4 | 6 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Offense - Receiving - Yards | 6.50 | 7.99 | 8.50 | 8.00 | 6 | 4 | Over |
| Carolina vs. Seattle | Hayden Hurst | Offense - Receiving - Yards | 30.50 | 37.48 | 37.00 | 39.00 | 7 | 3 | Over |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Yards | 230.50 | 177.76 | 178.60 | 184.50 | 0 | 10 | Under |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Fantasy Points - PrizePicks | 14.50 | 17.80 | 16.99 | 17.50 | 6 | 4 | Over |
| Buffalo vs. Washington | Jahan Dotson | Offense - Receiving - Receptions | 3.50 | 2.71 | 3.10 | 3.00 | 4 | 6 | Under |
| Houston vs. Jacksonville | Calvin Ridley | Fantasy Points - PrizePicks | 15.00 | 11.62 | 12.62 | 11.05 | 2 | 4 | Under |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Receiving - Receptions | 3.50 | 4.29 | 3.60 | 4.00 | 6 | 4 | Over |
| Chicago vs. Kansas City | Khalil Herbert | Fantasy Points - PrizePicks | 8.50 | 6.60 | 6.74 | 5.55 | 3 | 7 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing - Yards | 232.50 | 180.86 | 179.43 | 161.00 | 1 | 6 | Under |
| Buffalo vs. Washington | Josh Allen | Offense - Rushing - Yards | 30.50 | 37.20 | 36.80 | 31.00 | 5 | 5 | Over |
| Atlanta vs. Detroit | Drake London | Fantasy Points - PrizePicks | 11.00 | 8.59 | 7.90 | 7.85 | 4 | 6 | Under |
| LA Chargers vs. Minnesota | Mike Williams | Fantasy Points - PrizePicks | 14.00 | 10.98 | 10.47 | 9.15 | 3 | 7 | Under |
| Buffalo vs. Washington | James Cook | Offense - Rushing - Yards | 54.50 | 42.87 | 43.60 | 42.00 | 3 | 7 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Rushing - Yards | 15.50 | 18.80 | 18.20 | 17.00 | 6 | 4 | Over |
| New England vs. NY Jets | Tyler Conklin | Offense - Receiving - Receptions | 2.50 | 1.97 | 2.70 | 2.00 | 4 | 6 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Fantasy Points - PrizePicks | 11.50 | 9.09 | 7.94 | 11.36 | 0 | 3 | Under |
| Carolina vs. Seattle | Adam Thielen | Offense - Receiving - Yards | 37.50 | 29.70 | 31.10 | 26.00 | 4 | 6 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Rushing - Attempts | 8.50 | 6.73 | 6.20 | 7.50 | 5 | 5 | Under |
| Dallas vs. Arizona | Marquise Brown | Fantasy Points - PrizePicks | 10.50 | 8.33 | 8.66 | 7.45 | 2 | 8 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Rushing - Yards | 60.50 | 73.00 | 71.60 | 63.00 | 6 | 4 | Over |
| Philadelphia vs. Tampa Bay | A.J. Brown | Offense - Receiving - Yards | 68.50 | 82.60 | 84.00 | 87.00 | 7 | 3 | Over |
| Dallas vs. Arizona | CeeDee Lamb | Offense - Rushing and Receiving Yards | 74.50 | 89.82 | 91.10 | 97.00 | 7 | 3 | Over |
| Pittsburgh vs. Las Vegas | T.J. Watt | Defense - Sacks | 0.75 | 0.60 | 0.75 | 0.50 | 4 | 6 | Under |
| Houston vs. Jacksonville | Brandon McManus | Special Teams - Field Goals Made | 1.50 | 1.20 | 1.40 | 1.00 | 3 | 7 | Under |
| Houston vs. Jacksonville | Travis Etienne | Offense - Receiving - Receptions | 2.50 | 2.00 | 2.20 | 2.50 | 5 | 5 | Under |
| Chicago vs. Kansas City | Marquez Valdes-Scantling | Offense - Receiving - Yards | 27.50 | 33.00 | 39.80 | 27.50 | 5 | 5 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Rushing - Yards | 4.50 | 3.60 | 3.90 | 3.00 | 2 | 8 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Interceptions | 0.50 | 0.60 | 0.70 | 0.50 | 5 | 5 | Under |
| Atlanta vs. Detroit | Desmond Ridder | Offense - Rushing - Yards | 13.50 | 10.80 | 12.60 | 9.00 | 1 | 4 | Under |
| LA Rams vs. Cincinnati | Matthew Stafford | Offense - Passing - Interceptions | 0.50 | 0.60 | 0.80 | 0.50 | 5 | 5 | Under |
| Tennessee vs. Cleveland | Dustin Hopkins | Special Teams - Field Goals Made | 1.50 | 1.80 | 1.80 | 1.50 | 5 | 5 | Over |
| Philadelphia vs. Tampa Bay | Jake Elliott | Special Teams - Field Goals Made | 1.50 | 1.80 | 1.90 | 1.50 | 5 | 5 | Over |
| Buffalo vs. Washington | Tyler Bass | Special Teams - Field Goals Made | 1.50 | 1.80 | 1.80 | 1.50 | 5 | 5 | Over |
| Tennessee vs. Cleveland | Nick Folk | Special Teams - Field Goals Made | 1.50 | 1.80 | 2.20 | 1.50 | 5 | 5 | Over |
| LA Chargers vs. Minnesota | Keenan Allen | Offense - Receiving - Yards | 68.50 | 82.20 | 81.20 | 87.00 | 7 | 3 | Over |
| Pittsburgh vs. Las Vegas | George Pickens | Fantasy Points - PrizePicks | 11.50 | 9.21 | 9.37 | 9.25 | 4 | 6 | Under |
| Pittsburgh vs. Las Vegas | Davante Adams | Fantasy Points - PrizePicks | 15.50 | 12.42 | 16.34 | 10.35 | 4 | 6 | Under |
| Dallas vs. Arizona | James Conner | Offense - Rushing and Receiving Yards | 76.50 | 91.58 | 91.20 | 88.50 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | George Pickens | Offense - Receiving - Receptions | 4.00 | 3.22 | 3.10 | 3.00 | 2 | 8 | Under |
| New England vs. NY Jets | Hunter Henry | Fantasy Points - PrizePicks | 8.50 | 6.87 | 6.50 | 7.10 | 2 | 8 | Under |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Rushing - Yards | 13.50 | 16.08 | 16.80 | 14.50 | 5 | 5 | Over |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing and Rushing Yards | 262.50 | 212.57 | 210.86 | 199.00 | 2 | 5 | Under |
| LA Chargers vs. Minnesota | Gerald Everett | Offense - Receiving - Yards | 32.50 | 26.40 | 34.40 | 22.00 | 3 | 7 | Under |
| Philadelphia vs. Tampa Bay | Dallas Goedert | Offense - Receiving - Yards | 38.50 | 45.69 | 44.80 | 45.50 | 6 | 4 | Over |
| Denver vs. Miami | Raheem Mostert | Offense - Rushing - Yards | 60.50 | 49.20 | 54.00 | 41.00 | 4 | 6 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Rushing - Yards | 57.50 | 46.80 | 50.70 | 39.00 | 2 | 8 | Under |
| Houston vs. Jacksonville | Evan Engram | Offense - Receiving - Yards | 40.50 | 48.00 | 58.70 | 40.00 | 5 | 5 | Over |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Receiving - Yards | 17.50 | 20.74 | 20.10 | 19.00 | 5 | 5 | Over |
| Buffalo vs. Washington | Sam Howell | Offense - Passing - Yards | 223.50 | 183.74 | 185.50 | 185.50 | 0 | 2 | Under |
| New Orleans vs. Green Bay | Rashid Shaheed | Offense - Receiving - Yards | 40.50 | 47.53 | 48.60 | 47.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Pat Freiermuth | Fantasy Points - PrizePicks | 8.50 | 7.03 | 6.48 | 6.20 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | DeVonta Smith | Offense - Receiving - Receptions | 5.00 | 5.85 | 5.80 | 5.50 | 5 | 5 | Over |
| New England vs. NY Jets | Rhamondre Stevenson | Fantasy Points - PrizePicks | 14.50 | 12.04 | 10.90 | 11.00 | 2 | 8 | Under |
| Dallas vs. Arizona | Tony Pollard | Fantasy Points - PrizePicks | 17.00 | 14.16 | 14.62 | 11.80 | 4 | 6 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Touchdowns | 1.50 | 1.75 | 1.80 | 2.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing - Yards | 224.50 | 187.27 | 186.50 | 196.00 | 3 | 7 | Under |
| New England vs. NY Jets | DeVante Parker | Offense - Receiving - Yards | 34.50 | 28.80 | 37.40 | 24.00 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Attempts | 34.50 | 28.84 | 28.80 | 30.50 | 3 | 7 | Under |
| Denver vs. Miami | Samaje Perine | Offense - Receiving - Yards | 16.50 | 13.80 | 18.10 | 11.50 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | K.J. Osborn | Offense - Receiving - Yards | 36.50 | 30.60 | 48.10 | 25.50 | 4 | 6 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Fantasy Points - PrizePicks | 15.00 | 12.58 | 12.06 | 12.72 | 2 | 8 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Rushing - Yards | 16.50 | 19.11 | 20.40 | 19.00 | 7 | 3 | Over |
| Indianapolis vs. Baltimore | Mark Andrews | Offense - Receiving - Receptions | 4.50 | 3.80 | 3.90 | 3.50 | 3 | 7 | Under |
| Pittsburgh vs. Las Vegas | Pat Freiermuth | Offense - Receiving - Yards | 32.50 | 37.57 | 36.80 | 36.00 | 7 | 3 | Over |
| Atlanta vs. Detroit | Desmond Ridder | Offense - Passing - Yards | 195.50 | 165.00 | 164.60 | 169.00 | 2 | 3 | Under |
| New England vs. NY Jets | Zach Wilson | Offense - Passing - Attempts | 29.50 | 24.90 | 26.30 | 23.50 | 3 | 7 | Under |
| Buffalo vs. Washington | Stefon Diggs | Fantasy Points - PrizePicks | 15.50 | 13.09 | 12.77 | 13.85 | 4 | 6 | Under |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Rushing - Yards | 72.50 | 83.70 | 84.60 | 95.50 | 6 | 4 | Over |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Rushing - Attempts | 16.50 | 19.05 | 19.80 | 18.00 | 8 | 2 | Over |
| Pittsburgh vs. Las Vegas | Davante Adams | Offense - Receiving - Yards | 76.50 | 88.20 | 92.40 | 73.50 | 4 | 6 | Over |
| Denver vs. Miami | Courtland Sutton | Offense - Receiving - Receptions | 3.50 | 4.04 | 3.70 | 4.00 | 6 | 4 | Over |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Receiving - Yards | 8.50 | 7.21 | 5.70 | 0.00 | 2 | 8 | Under |
| Denver vs. Miami | Raheem Mostert | Offense - Rushing and Receiving Yards | 78.50 | 66.60 | 66.10 | 55.50 | 3 | 7 | Under |
| Atlanta vs. Detroit | Amon-Ra St. Brown | Offense - Rushing and Receiving Yards | 75.50 | 86.82 | 86.00 | 78.00 | 6 | 4 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Touchdowns | 1.50 | 1.72 | 1.90 | 1.50 | 5 | 5 | Over |
| Dallas vs. Arizona | Dak Prescott | Fantasy Points - PrizePicks | 16.50 | 18.94 | 18.30 | 16.61 | 5 | 5 | Over |
| Atlanta vs. Detroit | Amon-Ra St. Brown | Offense - Receiving - Yards | 73.50 | 84.12 | 83.30 | 76.00 | 6 | 4 | Over |
| Indianapolis vs. Baltimore | Michael Pittman | Offense - Receiving - Yards | 58.50 | 50.05 | 49.40 | 47.00 | 4 | 6 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Passing - Completions | 22.50 | 19.27 | 20.70 | 21.00 | 3 | 7 | Under |
| LA Rams vs. Cincinnati | Tyler Higbee | Offense - Receiving - Yards | 31.50 | 36.00 | 35.70 | 30.00 | 5 | 5 | Over |
| Indianapolis vs. Baltimore | Kylen Granson | Offense - Receiving - Yards | 24.50 | 21.00 | 23.60 | 17.50 | 4 | 6 | Under |
| Buffalo vs. Washington | Sam Howell | Offense - Passing and Rushing Yards | 241.50 | 207.07 | 208.50 | 208.50 | 0 | 2 | Under |
| Dallas vs. Arizona | Marquise Brown | Offense - Receiving - Yards | 41.50 | 47.41 | 48.60 | 51.50 | 6 | 4 | Over |
| Denver vs. Miami | Javonte Williams | Fantasy Points - PrizePicks | 11.50 | 9.88 | 9.27 | 8.35 | 2 | 8 | Under |
| Buffalo vs. Washington | Gabriel Davis | Offense - Receiving - Yards | 40.50 | 46.20 | 47.10 | 38.50 | 4 | 6 | Over |
| New Orleans vs. Green Bay | Juwan Johnson | Offense - Receiving - Yards | 29.50 | 33.65 | 34.20 | 39.00 | 6 | 4 | Over |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Rushing - Yards | 26.50 | 30.23 | 31.43 | 31.00 | 4 | 3 | Over |
| Denver vs. Miami | Jerry Jeudy | Fantasy Points - PrizePicks | 11.50 | 13.11 | 12.80 | 12.10 | 5 | 5 | Over |
| Indianapolis vs. Baltimore | Mark Andrews | Offense - Receiving - Yards | 53.50 | 46.02 | 46.50 | 47.50 | 3 | 7 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Completions | 21.50 | 18.50 | 18.00 | 20.50 | 3 | 7 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Rushing - Attempts | 2.50 | 2.85 | 3.00 | 3.00 | 7 | 3 | Over |
| Carolina vs. Seattle | Andy Dalton | Fantasy Points - PrizePicks | 13.00 | 11.20 | 11.86 | 11.47 | 4 | 6 | Under |
| Indianapolis vs. Baltimore | Rashod Bateman | Offense - Receiving - Yards | 36.50 | 41.50 | 42.60 | 38.50 | 5 | 5 | Over |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Rushing - Attempts | 9.50 | 10.80 | 10.60 | 9.00 | 4 | 6 | Over |
| Denver vs. Miami | Tyreek Hill | Offense - Receiving - Receptions | 6.50 | 5.62 | 6.10 | 5.50 | 4 | 6 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing and Rushing Yards | 237.50 | 205.54 | 204.50 | 219.50 | 3 | 7 | Under |
| Pittsburgh vs. Las Vegas | Daniel Carlson | Special Teams - Field Goals Made | 1.50 | 1.70 | 1.70 | 2.00 | 6 | 4 | Over |
| Buffalo vs. Washington | Gabriel Davis | Offense - Receiving - Receptions | 3.00 | 3.40 | 3.40 | 3.00 | 4 | 6 | Under |
| Chicago vs. Kansas City | Harrison Butker | Special Teams - Field Goals Made | 1.50 | 1.70 | 1.70 | 1.50 | 5 | 5 | Over |
| Houston vs. Jacksonville | Robert Woods | Offense - Receiving - Yards | 37.50 | 32.52 | 32.80 | 34.50 | 5 | 5 | Under |
| Carolina vs. Seattle | Miles Sanders | Fantasy Points - PrizePicks | 13.00 | 11.28 | 12.05 | 9.40 | 3 | 7 | Under |
| Philadelphia vs. Tampa Bay | Cade Otton | Offense - Receiving - Yards | 26.50 | 23.01 | 22.20 | 19.50 | 4 | 6 | Under |
| Denver vs. Miami | Adam Trautman | Offense - Receiving - Yards | 18.50 | 16.09 | 15.50 | 16.50 | 3 | 7 | Under |
| Philadelphia vs. Tampa Bay | Dallas Goedert | Fantasy Points - PrizePicks | 9.50 | 8.26 | 8.13 | 7.70 | 2 | 8 | Under |
| Tennessee vs. Cleveland | David Njoku | Fantasy Points - PrizePicks | 8.00 | 6.96 | 7.21 | 5.80 | 4 | 6 | Under |
| Dallas vs. Arizona | Tony Pollard | Offense - Rushing and Receiving Yards | 95.50 | 83.12 | 82.70 | 81.00 | 3 | 7 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing - Completions | 25.50 | 28.77 | 27.10 | 25.00 | 4 | 6 | Over |
| Chicago vs. Kansas City | Noah Gray | Offense - Receiving - Yards | 16.50 | 18.60 | 20.30 | 15.50 | 4 | 6 | Over |
| Denver vs. Miami | Tyreek Hill | Fantasy Points - PrizePicks | 18.00 | 15.71 | 17.07 | 13.30 | 3 | 7 | Under |
| Chicago vs. Kansas City | Travis Kelce | Fantasy Points - PrizePicks | 16.50 | 14.41 | 15.14 | 14.00 | 3 | 7 | Under |
| Denver vs. Miami | Russell Wilson | Fantasy Points - PrizePicks | 15.50 | 17.46 | 16.06 | 14.98 | 3 | 7 | Over |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Completions | 21.50 | 24.21 | 23.20 | 22.50 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing - Touchdowns | 1.50 | 1.69 | 1.60 | 2.00 | 6 | 4 | Over |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Attempts | 32.50 | 36.59 | 35.80 | 34.00 | 7 | 3 | Over |
| Denver vs. Miami | Tua Tagovailoa | Offense - Rushing - Attempts | 2.50 | 2.19 | 2.50 | 2.00 | 5 | 5 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Rushing - Attempts | 3.50 | 3.07 | 3.20 | 3.50 | 5 | 5 | Under |
| Pittsburgh vs. Las Vegas | Allen Robinson | Fantasy Points - PrizePicks | 8.50 | 7.46 | 7.56 | 7.15 | 4 | 6 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Passing - Yards | 264.50 | 296.90 | 297.90 | 297.00 | 7 | 3 | Over |
| Buffalo vs. Washington | Sam Howell | Fantasy Points - PrizePicks | 15.00 | 16.83 | 17.72 | 17.72 | 2 | 0 | Over |
| Tennessee vs. Cleveland | David Njoku | Offense - Receiving - Yards | 30.50 | 34.20 | 36.30 | 28.50 | 4 | 6 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Fantasy Points - PrizePicks | 14.50 | 16.24 | 15.88 | 16.71 | 7 | 3 | Over |
| Houston vs. Jacksonville | Christian Kirk | Offense - Receiving - Receptions | 5.00 | 4.40 | 4.80 | 5.50 | 5 | 5 | Under |
| Atlanta vs. Detroit | Marvin Jones | Offense - Receiving - Yards | 22.50 | 25.19 | 24.10 | 21.50 | 3 | 7 | Over |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing - Completions | 19.50 | 17.18 | 16.43 | 16.00 | 1 | 6 | Under |
| Buffalo vs. Washington | Josh Allen | Fantasy Points - PrizePicks | 20.50 | 22.92 | 21.89 | 21.67 | 6 | 4 | Over |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Yards | 236.50 | 208.60 | 210.40 | 182.50 | 2 | 8 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Rushing - Attempts | 14.50 | 16.20 | 14.90 | 14.50 | 5 | 5 | Over |
| Indianapolis vs. Baltimore | Gus Edwards | Offense - Rushing - Yards | 48.50 | 42.80 | 43.80 | 45.50 | 5 | 5 | Under |
| New England vs. NY Jets | Mac Jones | Fantasy Points - PrizePicks | 13.50 | 15.08 | 14.95 | 14.36 | 5 | 5 | Over |
| Tennessee vs. Cleveland | Amari Cooper | Offense - Receiving - Yards | 58.50 | 65.27 | 64.40 | 54.50 | 4 | 6 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Interceptions | 0.50 | 0.55 | 0.60 | 0.00 | 4 | 6 | Under |
| New England vs. NY Jets | Mike Gesicki | Offense - Receiving - Yards | 20.50 | 18.26 | 17.50 | 16.50 | 4 | 6 | Under |
| LA Chargers vs. Minnesota | T.J. Hockenson | Offense - Receiving - Yards | 52.50 | 46.80 | 56.80 | 39.00 | 4 | 6 | Under |
| LA Chargers vs. Minnesota | Keenan Allen | Offense - Receiving - Receptions | 6.50 | 7.20 | 7.20 | 6.00 | 4 | 6 | Over |
| Houston vs. Jacksonville | Calvin Ridley | Offense - Receiving - Receptions | 5.50 | 6.08 | 6.50 | 7.00 | 4 | 2 | Over |
| Denver vs. Miami | Samaje Perine | Offense - Receiving - Receptions | 2.50 | 2.76 | 2.80 | 3.00 | 6 | 4 | Over |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing - Completions | 20.50 | 18.35 | 19.40 | 20.50 | 5 | 5 | Under |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Rushing - Attempts | 8.50 | 7.61 | 8.60 | 8.00 | 5 | 5 | Under |
| Carolina vs. Seattle | Andy Dalton | Offense - Passing - Yards | 213.50 | 191.38 | 192.50 | 204.50 | 3 | 7 | Under |
| Houston vs. Jacksonville | Calvin Ridley | Offense - Receiving - Yards | 69.50 | 62.36 | 63.67 | 62.00 | 2 | 4 | Under |
| Atlanta vs. Detroit | Amon-Ra St. Brown | Fantasy Points - PrizePicks | 15.50 | 13.92 | 14.65 | 11.60 | 4 | 6 | Under |
| Carolina vs. Seattle | Kenneth Walker III | Fantasy Points - PrizePicks | 13.50 | 12.12 | 12.74 | 12.20 | 3 | 7 | Under |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing - Attempts | 27.50 | 24.70 | 24.00 | 22.00 | 2 | 8 | Under |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Yards | 211.50 | 233.00 | 232.00 | 237.50 | 6 | 4 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing - Yards | 177.50 | 159.58 | 158.90 | 152.50 | 3 | 7 | Under |
| Dallas vs. Arizona | CeeDee Lamb | Offense - Receiving - Receptions | 6.00 | 6.60 | 6.70 | 5.50 | 4 | 6 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Attempts | 30.50 | 33.55 | 33.60 | 34.00 | 6 | 4 | Over |
| Indianapolis vs. Baltimore | Michael Pittman | Fantasy Points - PrizePicks | 12.50 | 11.26 | 10.44 | 10.50 | 4 | 6 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Attempts | 29.50 | 26.62 | 27.90 | 26.00 | 4 | 6 | Under |
| Dallas vs. Arizona | James Conner | Offense - Rushing - Attempts | 14.50 | 15.91 | 15.20 | 15.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Rushing and Receiving Yards | 48.50 | 43.80 | 44.50 | 36.50 | 4 | 6 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Rushing - Attempts | 3.50 | 3.84 | 4.00 | 4.50 | 6 | 4 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Rushing - Yards | 9.50 | 8.59 | 9.20 | 7.50 | 3 | 7 | Under |
| Chicago vs. Kansas City | Travis Kelce | Offense - Receiving - Receptions | 6.50 | 5.89 | 6.80 | 6.00 | 4 | 6 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Receiving - Yards | 22.50 | 20.40 | 26.80 | 17.00 | 5 | 5 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Completions | 21.00 | 22.89 | 21.90 | 23.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Allen Robinson | Offense - Receiving - Receptions | 3.50 | 3.81 | 3.70 | 4.00 | 6 | 4 | Over |
| Atlanta vs. Detroit | Mack Hollins | Offense - Receiving - Yards | 30.50 | 33.19 | 32.30 | 33.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Receiving - Receptions | 2.50 | 2.72 | 2.40 | 2.50 | 5 | 5 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Rushing - Yards | 64.50 | 70.04 | 71.60 | 63.50 | 4 | 6 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Receiving - Yards | 10.50 | 11.40 | 14.30 | 9.50 | 4 | 6 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Receiving - Yards | 10.50 | 9.60 | 11.90 | 8.00 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing and Rushing Yards | 287.50 | 263.23 | 264.80 | 259.00 | 4 | 6 | Under |
| Carolina vs. Seattle | Tyler Lockett | Fantasy Points - PrizePicks | 12.50 | 11.45 | 11.41 | 12.55 | 5 | 5 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing - Completions | 25.50 | 23.36 | 24.20 | 24.50 | 5 | 5 | Under |
| Dallas vs. Arizona | James Conner | Fantasy Points - PrizePicks | 13.00 | 14.09 | 15.02 | 14.55 | 5 | 5 | Over |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Rushing - Attempts | 13.50 | 12.37 | 11.50 | 11.00 | 3 | 7 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Rushing and Receiving Yards | 85.50 | 78.40 | 77.50 | 80.00 | 3 | 7 | Under |
| Denver vs. Miami | Javonte Williams | Offense - Rushing and Receiving Yards | 67.50 | 62.04 | 61.70 | 62.00 | 4 | 6 | Under |
| Houston vs. Jacksonville | Trevor Lawrence | Fantasy Points - PrizePicks | 17.50 | 18.91 | 19.58 | 18.50 | 6 | 4 | Over |
| Carolina vs. Seattle | Tyler Lockett | Offense - Receiving - Receptions | 4.50 | 4.86 | 4.60 | 4.50 | 5 | 5 | Over |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Completions | 21.50 | 23.22 | 23.30 | 24.00 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Jakobi Meyers | Offense - Receiving - Yards | 49.50 | 53.46 | 53.00 | 50.50 | 5 | 5 | Over |
| Indianapolis vs. Baltimore | Michael Pittman | Offense - Receiving - Receptions | 5.50 | 5.93 | 5.60 | 6.00 | 6 | 4 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Fantasy Points - PrizePicks | 13.00 | 11.99 | 13.07 | 12.79 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing - Attempts | 37.50 | 40.38 | 38.90 | 39.50 | 5 | 5 | Over |
| Dallas vs. Arizona | Zach Ertz | Fantasy Points - PrizePicks | 9.00 | 8.33 | 8.68 | 9.15 | 5 | 5 | Under |
| Dallas vs. Arizona | Tony Pollard | Offense - Receiving - Yards | 17.50 | 16.20 | 27.20 | 13.50 | 4 | 6 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Fantasy Points - PrizePicks | 24.00 | 22.25 | 21.65 | 20.19 | 2 | 8 | Under |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Rushing and Receiving Yards | 70.50 | 65.37 | 64.50 | 61.00 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | Chris Godwin | Fantasy Points - PrizePicks | 13.00 | 12.07 | 13.00 | 11.90 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | Mike Williams | Offense - Receiving - Yards | 64.50 | 69.08 | 68.20 | 71.50 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Allen Robinson | Offense - Receiving - Yards | 35.50 | 38.01 | 39.10 | 45.50 | 6 | 4 | Over |
| LA Chargers vs. Minnesota | Justin Jefferson | Offense - Rushing and Receiving Yards | 102.50 | 95.46 | 95.70 | 89.50 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | Justin Jefferson | Offense - Receiving - Yards | 101.50 | 94.57 | 94.60 | 85.00 | 5 | 5 | Under |
| Buffalo vs. Washington | Stefon Diggs | Offense - Receiving - Receptions | 6.00 | 5.59 | 5.70 | 6.00 | 5 | 5 | Under |
| New England vs. NY Jets | Garrett Wilson | Fantasy Points - PrizePicks | 11.50 | 10.73 | 11.44 | 11.85 | 6 | 4 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing - Attempts | 38.50 | 35.92 | 37.20 | 38.00 | 5 | 5 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Rushing - Yards | 13.50 | 14.40 | 13.67 | 12.00 | 1 | 2 | Over |
| Tennessee vs. Cleveland | Amari Cooper | Offense - Receiving - Receptions | 4.50 | 4.20 | 4.20 | 3.50 | 3 | 7 | Under |
| New Orleans vs. Green Bay | Michael Thomas | Fantasy Points - PrizePicks | 12.00 | 12.80 | 12.93 | 12.05 | 2 | 2 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Yards | 194.50 | 207.29 | 208.70 | 189.50 | 5 | 5 | Over |
| Houston vs. Jacksonville | Travis Etienne | Offense - Rushing and Receiving Yards | 88.50 | 82.69 | 81.90 | 92.00 | 5 | 5 | Under |
| New Orleans vs. Green Bay | Chris Olave | Offense - Receiving - Receptions | 5.00 | 4.68 | 4.80 | 5.00 | 2 | 8 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Fantasy Points - PrizePicks | 23.00 | 24.46 | 23.86 | 23.88 | 6 | 4 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Rushing and Receiving Yards | 79.50 | 84.50 | 85.90 | 75.50 | 4 | 6 | Over |
| Dallas vs. Arizona | Marquise Brown | Offense - Receiving - Receptions | 4.00 | 4.25 | 4.60 | 4.50 | 5 | 5 | Under |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Rushing and Receiving Yards | 46.50 | 49.36 | 49.80 | 53.00 | 6 | 4 | Over |
| Houston vs. Jacksonville | Robert Woods | Offense - Receiving - Receptions | 3.50 | 3.72 | 3.70 | 4.00 | 6 | 4 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Rushing - Attempts | 15.50 | 16.42 | 17.00 | 14.50 | 4 | 6 | Over |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Rushing - Yards | 8.50 | 9.00 | 10.40 | 7.50 | 4 | 6 | Over |
| Denver vs. Miami | Tua Tagovailoa | Fantasy Points - PrizePicks | 17.50 | 18.53 | 19.66 | 17.01 | 5 | 5 | Over |
| Tennessee vs. Cleveland | Derrick Henry | Fantasy Points - PrizePicks | 15.00 | 15.87 | 16.07 | 15.45 | 5 | 5 | Over |
| Atlanta vs. Detroit | Jared Goff | Fantasy Points - PrizePicks | 17.50 | 18.49 | 17.23 | 16.22 | 5 | 5 | Over |
| Houston vs. Jacksonville | Travis Etienne | Offense - Rushing - Attempts | 15.50 | 14.63 | 13.70 | 15.00 | 5 | 5 | Under |
| Denver vs. Miami | Courtland Sutton | Offense - Receiving - Yards | 46.50 | 43.90 | 43.00 | 38.50 | 4 | 6 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing and Rushing Yards | 307.50 | 290.72 | 291.30 | 302.50 | 5 | 5 | Under |
| New England vs. NY Jets | Mac Jones | Offense - Passing and Rushing Yards | 224.50 | 236.73 | 235.70 | 236.50 | 6 | 4 | Over |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Completions | 20.50 | 21.62 | 20.30 | 20.00 | 5 | 5 | Over |
| Carolina vs. Seattle | Noah Fant | Offense - Receiving - Yards | 22.50 | 21.28 | 22.50 | 26.00 | 5 | 5 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Attempts | 32.50 | 34.24 | 35.00 | 35.50 | 7 | 3 | Over |
| Houston vs. Jacksonville | Travis Etienne | Offense - Rushing - Yards | 69.50 | 65.80 | 64.80 | 69.50 | 5 | 5 | Under |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing and Rushing Yards | 244.50 | 231.73 | 231.10 | 240.00 | 3 | 7 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Completions | 17.50 | 16.60 | 17.80 | 16.50 | 4 | 6 | Under |
| Pittsburgh vs. Las Vegas | Jakobi Meyers | Fantasy Points - PrizePicks | 10.50 | 11.04 | 11.01 | 9.20 | 5 | 5 | Over |
| Indianapolis vs. Baltimore | Kylen Granson | Offense - Receiving - Receptions | 2.50 | 2.63 | 2.40 | 2.50 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | Keenan Allen | Fantasy Points - PrizePicks | 16.00 | 15.19 | 14.06 | 13.00 | 2 | 8 | Under |
| Buffalo vs. Washington | Terry McLaurin | Fantasy Points - PrizePicks | 10.50 | 9.98 | 10.97 | 9.05 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | A.J. Brown | Fantasy Points - PrizePicks | 14.50 | 13.81 | 13.85 | 12.40 | 4 | 6 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing and Rushing Yards | 298.50 | 284.71 | 286.30 | 286.00 | 4 | 6 | Under |
| New Orleans vs. Green Bay | Michael Thomas | Offense - Receiving - Receptions | 5.00 | 5.23 | 5.25 | 5.00 | 1 | 3 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Fantasy Points - PrizePicks | 17.50 | 16.70 | 16.03 | 17.34 | 3 | 4 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Fantasy Points - PrizePicks | 20.00 | 19.09 | 17.63 | 18.46 | 3 | 7 | Under |
| Chicago vs. Kansas City | Travis Kelce | Offense - Receiving - Yards | 73.50 | 76.80 | 77.40 | 74.50 | 5 | 5 | Over |
| LA Chargers vs. Minnesota | Kirk Cousins | Fantasy Points - PrizePicks | 20.00 | 19.11 | 18.71 | 20.16 | 5 | 5 | Under |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Yards | 250.50 | 239.40 | 240.20 | 244.50 | 5 | 5 | Under |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Rushing - Yards | 47.50 | 45.44 | 44.40 | 38.50 | 3 | 7 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Rushing - Attempts | 3.50 | 3.65 | 4.40 | 4.00 | 5 | 5 | Under |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing and Rushing Yards | 243.50 | 233.35 | 234.50 | 249.00 | 6 | 4 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing - Yards | 284.50 | 272.80 | 273.20 | 273.00 | 5 | 5 | Under |
| New Orleans vs. Green Bay | Michael Thomas | Offense - Receiving - Yards | 55.50 | 57.76 | 58.00 | 59.00 | 3 | 1 | Over |
| LA Chargers vs. Minnesota | Justin Jefferson | Offense - Receiving - Receptions | 7.50 | 7.19 | 7.50 | 8.00 | 5 | 5 | Under |
| LA Rams vs. Cincinnati | Matthew Stafford | Offense - Passing - Yards | 252.50 | 242.38 | 242.10 | 251.00 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | Mike Williams | Offense - Receiving - Receptions | 5.00 | 4.80 | 4.90 | 4.00 | 4 | 6 | Under |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Receiving - Receptions | 2.50 | 2.40 | 3.00 | 2.00 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | A.J. Brown | Offense - Receiving - Receptions | 5.00 | 4.80 | 5.30 | 4.00 | 4 | 6 | Under |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing - Yards | 237.50 | 228.26 | 227.20 | 237.00 | 5 | 5 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing and Rushing Yards | 208.50 | 216.58 | 217.90 | 193.50 | 4 | 6 | Over |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing - Yards | 292.50 | 281.20 | 280.80 | 286.00 | 5 | 5 | Under |
| Houston vs. Jacksonville | Travis Etienne | Offense - Receiving - Yards | 16.50 | 15.87 | 17.10 | 17.50 | 6 | 4 | Under |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing and Rushing Yards | 242.50 | 251.70 | 250.90 | 254.00 | 6 | 4 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing - Completions | 16.50 | 15.88 | 15.30 | 14.50 | 4 | 6 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Passing - Attempts | 33.50 | 32.27 | 33.00 | 32.50 | 4 | 6 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing - Completions | 19.50 | 20.20 | 20.33 | 20.00 | 3 | 0 | Over |
| Chicago vs. Kansas City | D.J. Moore | Offense - Receiving - Receptions | 3.50 | 3.62 | 3.60 | 4.00 | 6 | 4 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing - Attempts | 30.50 | 29.43 | 28.43 | 29.00 | 2 | 5 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing - Attempts | 31.50 | 32.60 | 32.67 | 30.00 | 1 | 2 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Yards | 245.50 | 254.09 | 252.50 | 235.00 | 4 | 6 | Over |
| Pittsburgh vs. Las Vegas | George Pickens | Offense - Receiving - Yards | 50.50 | 48.83 | 49.90 | 55.00 | 6 | 4 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Passing - Attempts | 35.50 | 34.40 | 34.70 | 36.00 | 5 | 5 | Under |
| New England vs. NY Jets | Zach Wilson | Offense - Passing and Rushing Yards | 198.50 | 192.40 | 193.60 | 162.00 | 4 | 6 | Under |
| Atlanta vs. Detroit | Drake London | Offense - Receiving - Yards | 49.50 | 51.00 | 52.00 | 42.50 | 4 | 6 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Attempts | 33.50 | 34.51 | 35.40 | 34.50 | 5 | 5 | Over |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Completions | 21.50 | 20.92 | 21.60 | 22.50 | 6 | 4 | Under |
| Carolina vs. Seattle | Tyler Lockett | Offense - Receiving - Yards | 56.50 | 54.97 | 55.10 | 57.00 | 5 | 5 | Under |
| Pittsburgh vs. Las Vegas | Davante Adams | Offense - Receiving - Receptions | 6.00 | 5.84 | 5.80 | 6.50 | 5 | 5 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Attempts | 32.50 | 33.35 | 31.90 | 32.50 | 5 | 5 | Over |
| New England vs. NY Jets | Zach Wilson | Fantasy Points - PrizePicks | 10.50 | 10.23 | 11.46 | 9.88 | 5 | 5 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing - Completions | 25.50 | 24.87 | 26.10 | 30.50 | 6 | 4 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing and Rushing Yards | 270.50 | 263.83 | 265.20 | 272.50 | 5 | 5 | Under |
| Houston vs. Jacksonville | Christian Kirk | Offense - Receiving - Yards | 54.50 | 55.81 | 56.80 | 49.00 | 4 | 6 | Over |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing - Yards | 235.50 | 229.89 | 230.70 | 249.00 | 6 | 4 | Under |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing and Rushing Yards | 264.50 | 270.74 | 269.30 | 271.00 | 5 | 5 | Over |
| Denver vs. Miami | Tyreek Hill | Offense - Receiving - Yards | 85.50 | 87.49 | 89.00 | 75.00 | 3 | 7 | Over |
| New England vs. NY Jets | Kendrick Bourne | Offense - Receiving - Yards | 30.50 | 31.20 | 34.20 | 26.00 | 5 | 5 | Over |
| New England vs. NY Jets | Zach Wilson | Offense - Passing - Yards | 180.50 | 176.40 | 182.80 | 147.00 | 4 | 6 | Under |
| New Orleans vs. Green Bay | Derek Carr | Fantasy Points - PrizePicks | 14.50 | 14.18 | 14.91 | 17.46 | 7 | 3 | Under |
| Buffalo vs. Washington | Josh Allen | Offense - Passing and Rushing Yards | 284.50 | 278.20 | 277.00 | 271.00 | 4 | 6 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Yards | 249.50 | 244.00 | 244.80 | 245.50 | 5 | 5 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Completions | 20.50 | 20.07 | 19.60 | 19.00 | 4 | 6 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing and Rushing Yards | 248.50 | 253.73 | 254.90 | 270.50 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Rushing - Yards | 28.50 | 29.09 | 28.20 | 29.50 | 5 | 5 | Over |
| New England vs. NY Jets | Zach Wilson | Offense - Rushing - Attempts | 3.50 | 3.43 | 3.20 | 3.50 | 5 | 5 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Passing and Rushing Yards | 250.50 | 245.53 | 244.10 | 252.00 | 5 | 5 | Under |
| Tennessee vs. Cleveland | Chigoziem Okonkwo | Offense - Receiving - Yards | 33.50 | 34.15 | 35.00 | 38.00 | 6 | 4 | Over |
| Carolina vs. Seattle | Geno Smith | Fantasy Points - PrizePicks | 17.50 | 17.16 | 17.43 | 17.52 | 5 | 5 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Rushing - Attempts | 10.50 | 10.70 | 11.25 | 9.00 | 3 | 5 | Over |
| Buffalo vs. Washington | Jahan Dotson | Offense - Receiving - Yards | 44.50 | 43.70 | 45.40 | 41.50 | 4 | 6 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing and Rushing Yards | 197.50 | 194.00 | 194.67 | 211.00 | 2 | 1 | Under |
| Pittsburgh vs. Las Vegas | Pat Freiermuth | Offense - Receiving - Receptions | 3.50 | 3.44 | 3.20 | 3.00 | 3 | 7 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing - Completions | 20.50 | 20.16 | 18.90 | 19.00 | 4 | 6 | Under |
| Buffalo vs. Washington | Stefon Diggs | Offense - Receiving - Yards | 71.50 | 70.31 | 69.50 | 68.50 | 5 | 5 | Under |
| Houston vs. Jacksonville | Nico Collins | Offense - Receiving - Yards | 54.50 | 53.61 | 53.50 | 48.50 | 4 | 6 | Under |
| LA Rams vs. Cincinnati | Van Jefferson | Offense - Receiving - Yards | 37.50 | 38.11 | 39.30 | 35.50 | 5 | 5 | Over |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing and Rushing Yards | 295.50 | 290.69 | 289.40 | 291.00 | 5 | 5 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Rushing and Receiving Yards | 80.50 | 79.20 | 78.00 | 66.00 | 4 | 6 | Under |
| Houston vs. Jacksonville | Dameon Pierce | Fantasy Points - PrizePicks | 10.50 | 10.33 | 10.45 | 11.50 | 7 | 3 | Under |
| LA Chargers vs. Minnesota | Donald Parham | Offense - Receiving - Yards | 17.50 | 17.78 | 18.70 | 17.00 | 5 | 5 | Over |
| Atlanta vs. Detroit | Kyle Pitts | Offense - Receiving - Yards | 33.50 | 33.00 | 38.10 | 27.50 | 4 | 6 | Under |
| Philadelphia vs. Tampa Bay | DeVonta Smith | Fantasy Points - PrizePicks | 14.50 | 14.29 | 14.31 | 15.00 | 6 | 4 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Yards | 233.50 | 236.80 | 238.20 | 258.50 | 6 | 4 | Over |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing - Attempts | 31.50 | 31.90 | 30.80 | 29.50 | 4 | 6 | Over |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Yards | 230.50 | 227.66 | 225.90 | 234.50 | 5 | 5 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Passing - Yards | 267.50 | 264.57 | 265.00 | 252.50 | 3 | 7 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing - Yards | 283.50 | 280.40 | 279.00 | 273.50 | 3 | 7 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Passing - Completions | 23.50 | 23.25 | 23.10 | 23.00 | 3 | 7 | Under |
| Houston vs. Jacksonville | Dameon Pierce | Offense - Receiving - Yards | 13.50 | 13.62 | 13.10 | 11.50 | 5 | 5 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Completions | 23.50 | 23.29 | 23.60 | 24.00 | 6 | 4 | Under |
| Chicago vs. Kansas City | Chase Claypool | Offense - Receiving - Yards | 22.50 | 22.69 | 22.60 | 20.50 | 5 | 5 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Receiving - Yards | 15.50 | 15.60 | 16.30 | 13.00 | 4 | 6 | Over |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing - Attempts | 35.50 | 35.29 | 36.00 | 40.00 | 6 | 4 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Attempts | 30.50 | 30.67 | 30.30 | 29.50 | 5 | 5 | Over |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing - Attempts | 31.50 | 31.35 | 32.40 | 34.50 | 6 | 4 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing - Yards | 180.50 | 179.67 | 181.00 | 179.00 | 1 | 2 | Under |
| New Orleans vs. Green Bay | Chris Olave | Offense - Receiving - Yards | 65.50 | 65.20 | 65.90 | 61.00 | 3 | 7 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Touchdowns | 1.50 | 1.51 | 1.30 | 1.50 | 5 | 5 | Under |
| Dallas vs. Arizona | CeeDee Lamb | Fantasy Points - PrizePicks | 16.00 | 15.94 | 15.46 | 15.15 | 4 | 6 | Under |
| Dallas vs. Arizona | Michael Gallup | Offense - Receiving - Yards | 25.50 | 25.59 | 26.90 | 29.50 | 5 | 5 | Over |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Rushing - Attempts | 3.50 | 3.51 | 3.50 | 3.00 | 4 | 6 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Rushing - Attempts | 3.50 | 3.49 | 3.50 | 3.00 | 5 | 5 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Rushing - Yards | 45.50 | 45.60 | 54.40 | 38.00 | 4 | 6 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing - Interceptions | 0.50 | 0.50 | 0.40 | 0.00 | 3 | 7 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Rushing - Attempts | 5.50 | 5.51 | 5.86 | 6.00 | 5 | 2 | Under |
| Chicago vs. Kansas City | D.J. Moore | Fantasy Points - PrizePicks | 10.50 | 10.49 | 11.12 | 10.35 | 5 | 5 | Under |
| Denver vs. Miami | Javonte Williams | Offense - Rushing - Yards | 49.50 | 49.52 | 48.90 | 49.00 | 5 | 5 | Over |
| Carolina vs. Seattle | Brian Burns | Defense - Sacks | 0.75 | 0.75 | 0.75 | 0.75 | 5 | 5 | Over |
| Game | Player Name | Prop | Line | Projection | Robot Likes |
|---|---|---|---|---|---|
| Pittsburgh vs. Las Vegas | Maxx Crosby | Defense - Sacks | 0.25 | 0.80 | Over |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Receiving - Yards | 12.50 | 30.62 | Over |
| LA Chargers vs. Minnesota | Danielle Hunter | Defense - Sacks | 0.25 | 0.60 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Receiving - Yards | 8.50 | 19.20 | Over |
| New England vs. NY Jets | Dalvin Cook | Offense - Receiving - Yards | 7.50 | 15.60 | Over |
| New England vs. NY Jets | Dalvin Cook | Offense - Rushing - Yards | 26.50 | 53.91 | Over |
| Buffalo vs. Washington | Sam Howell | Offense - Passing - Interceptions | 0.50 | 1.00 | Over |
| Denver vs. Miami | Jaelan Phillips | Defense - Sacks | 0.25 | 0.50 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Fantasy Points - PrizePicks | 10.50 | 0.12 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing and Rushing Yards | 229.50 | 6.60 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing - Completions | 20.50 | 0.60 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing - Yards | 215.50 | 6.60 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Offense - Rushing - Yards | 24.50 | 48.17 | Over |
| Denver vs. Miami | Brandon Johnson | Offense - Receiving - Yards | 19.50 | 1.20 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Offense - Rushing and Receiving Yards | 60.50 | 3.77 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Passing - Attempts | 32.50 | 2.40 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Offense - Rushing - Yards | 45.50 | 3.73 | Under |
| New England vs. NY Jets | Dalvin Cook | Offense - Rushing and Receiving Yards | 38.50 | 73.79 | Over |
| Dallas vs. Arizona | Rondale Moore | Offense - Receiving - Yards | 24.50 | 46.88 | Over |
| Chicago vs. Kansas City | Jerick McKinnon | Offense - Receiving - Yards | 13.50 | 25.80 | Over |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Receiving - Yards | 14.50 | 1.39 | Under |
| Tennessee vs. Cleveland | Jerome Ford | Offense - Rushing - Attempts | 12.50 | 1.32 | Under |
| Indianapolis vs. Baltimore | Zack Moss | Fantasy Points - PrizePicks | 11.50 | 1.50 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Fantasy Points - PrizePicks | 13.00 | 1.80 | Under |
| Indianapolis vs. Baltimore | Gardner Minshew | Offense - Rushing - Yards | 10.50 | 1.49 | Under |
| Dallas vs. Arizona | Rico Dowdle | Offense - Rushing - Yards | 27.50 | 4.41 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Rushing - Yards | 3.50 | 0.60 | Under |
| New Orleans vs. Green Bay | Jordan Love | Fantasy Points - PrizePicks | 14.50 | 2.56 | Under |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Receiving - Receptions | 2.50 | 0.45 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Receiving - Yards | 15.50 | 2.81 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Rushing and Receiving Yards | 56.50 | 102.00 | Over |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Rushing and Receiving Yards | 71.50 | 15.00 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Rushing and Receiving Yards | 70.50 | 16.80 | Under |
| New Orleans vs. Green Bay | Jordan Love | Offense - Passing - Yards | 211.50 | 50.40 | Under |
| Chicago vs. Kansas City | Darnell Mooney | Offense - Receiving - Yards | 29.50 | 51.86 | Over |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Rushing - Attempts | 14.50 | 3.60 | Under |
| Indianapolis vs. Baltimore | Zack Moss | Offense - Rushing - Yards | 54.50 | 15.00 | Under |
| New England vs. NY Jets | Mac Jones | Offense - Rushing - Yards | 8.50 | 2.40 | Under |
| Atlanta vs. Detroit | Tyler Allgeier | Offense - Rushing - Yards | 46.50 | 79.60 | Over |
| Buffalo vs. Washington | Sam Howell | Offense - Rushing - Yards | 12.50 | 21.40 | Over |
| Dallas vs. Arizona | Micah Parsons | Defense - Sacks | 1.00 | 0.30 | Under |
| Buffalo vs. Washington | Leonard Floyd | Defense - Sacks | 0.50 | 0.85 | Over |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Rushing - Yards | 49.50 | 15.00 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Rushing - Attempts | 11.50 | 3.60 | Under |
| LA Chargers vs. Minnesota | Alexander Mattison | Offense - Receiving - Receptions | 2.50 | 0.80 | Under |
| Chicago vs. Kansas City | Darnell Mooney | Offense - Receiving - Receptions | 2.50 | 4.16 | Over |
| Indianapolis vs. Baltimore | Gardner Minshew | Fantasy Points - PrizePicks | 14.50 | 4.87 | Under |
| LA Chargers vs. Minnesota | Joshua Kelley | Fantasy Points - PrizePicks | 13.00 | 4.38 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Rushing - Yards | 3.50 | 1.20 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Receiving - Yards | 15.50 | 5.40 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Offense - Rushing and Receiving Yards | 34.50 | 56.79 | Over |
| Denver vs. Miami | Durham Smythe | Offense - Receiving - Yards | 27.50 | 10.20 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Rushing - Yards | 44.50 | 72.46 | Over |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Receiving - Yards | 14.50 | 5.59 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Interceptions | 0.50 | 0.80 | Over |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Interceptions | 0.50 | 0.80 | Over |
| New England vs. NY Jets | Allen Lazard | Offense - Receiving - Yards | 30.50 | 48.76 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Rushing - Yards | 58.50 | 93.44 | Over |
| Atlanta vs. Detroit | Josh Reynolds | Offense - Receiving - Yards | 42.50 | 18.00 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Rushing - Yards | 12.50 | 5.33 | Under |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Rushing and Receiving Yards | 78.50 | 35.07 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Fantasy Points - PrizePicks | 6.50 | 10.10 | Over |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Receiving - Yards | 15.50 | 24.00 | Over |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Rushing - Attempts | 15.50 | 7.06 | Under |
| Dallas vs. Arizona | Jake Ferguson | Offense - Receiving - Yards | 23.50 | 10.80 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Receiving - Receptions | 1.50 | 2.31 | Over |
| Tennessee vs. Cleveland | Donovan Peoples-Jones | Offense - Receiving - Yards | 28.50 | 43.80 | Over |
| Dallas vs. Arizona | Jake Ferguson | Offense - Receiving - Receptions | 2.50 | 1.20 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Receiving - Receptions | 2.50 | 1.20 | Under |
| LA Chargers vs. Minnesota | Josh Palmer | Offense - Receiving - Receptions | 2.50 | 3.80 | Over |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Interceptions | 0.50 | 0.24 | Under |
| Denver vs. Miami | Raheem Mostert | Offense - Receiving - Yards | 13.50 | 6.60 | Under |
| Houston vs. Jacksonville | Dameon Pierce | Offense - Rushing - Yards | 43.50 | 65.64 | Over |
| Denver vs. Miami | Jerry Jeudy | Offense - Receiving - Yards | 49.50 | 74.64 | Over |
| New England vs. NY Jets | Breece Hall | Fantasy Points - PrizePicks | 9.50 | 14.32 | Over |
| LA Chargers vs. Minnesota | Josh Palmer | Offense - Receiving - Yards | 27.50 | 41.40 | Over |
| LA Chargers vs. Minnesota | Joshua Kelley | Offense - Rushing - Yards | 58.50 | 29.18 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing - Yards | 224.50 | 112.10 | Under |
| Pittsburgh vs. Las Vegas | Austin Hooper | Offense - Receiving - Yards | 20.50 | 30.73 | Over |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Touchdowns | 1.50 | 2.24 | Over |
| Indianapolis vs. Baltimore | Gus Edwards | Fantasy Points - PrizePicks | 9.50 | 4.87 | Under |
| Buffalo vs. Washington | James Cook | Offense - Receiving - Yards | 17.50 | 9.00 | Under |
| Philadelphia vs. Tampa Bay | Cade Otton | Fantasy Points - PrizePicks | 6.50 | 3.36 | Under |
| Buffalo vs. Washington | Dawson Knox | Offense - Receiving - Yards | 25.50 | 37.80 | Over |
| Indianapolis vs. Baltimore | Lamar Jackson | Fantasy Points - PrizePicks | 20.50 | 10.62 | Under |
| Chicago vs. Kansas City | Cole Kmet | Offense - Receiving - Yards | 28.50 | 42.01 | Over |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing - Attempts | 29.50 | 15.56 | Under |
| LA Rams vs. Cincinnati | Matthew Stafford | Offense - Passing - Touchdowns | 1.50 | 0.80 | Under |
| Indianapolis vs. Baltimore | Mark Andrews | Fantasy Points - PrizePicks | 12.50 | 6.70 | Under |
| LA Rams vs. Cincinnati | Tutu Atwell | Offense - Receiving - Yards | 55.50 | 30.00 | Under |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Receiving - Receptions | 1.50 | 0.83 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing and Rushing Yards | 278.50 | 154.40 | Under |
| New England vs. NY Jets | Randall Cobb | Offense - Receiving - Yards | 12.50 | 18.00 | Over |
| Tennessee vs. Cleveland | Elijah Moore | Offense - Receiving - Yards | 37.50 | 21.00 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Passing - Completions | 19.50 | 10.96 | Under |
| New England vs. NY Jets | Garrett Wilson | Offense - Receiving - Yards | 48.50 | 69.73 | Over |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Touchdowns | 1.50 | 2.14 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Rushing - Yards | 48.50 | 69.01 | Over |
| New England vs. NY Jets | Zach Wilson | Offense - Rushing - Yards | 13.50 | 7.80 | Under |
| Denver vs. Miami | Jerry Jeudy | Offense - Receiving - Receptions | 4.00 | 5.67 | Over |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Rushing - Yards | 17.50 | 10.20 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Rushing - Attempts | 2.50 | 3.51 | Over |
| Chicago vs. Kansas City | Justin Fields | Fantasy Points - PrizePicks | 18.00 | 25.26 | Over |
| Denver vs. Miami | Jason Sanders | Special Teams - Field Goals Made | 1.50 | 2.10 | Over |
| Carolina vs. Seattle | Andy Dalton | Offense - Passing - Interceptions | 0.50 | 0.69 | Over |
| Philadelphia vs. Tampa Bay | Chris Godwin | Offense - Receiving - Yards | 53.50 | 74.23 | Over |
| Tennessee vs. Cleveland | Amari Cooper | Fantasy Points - PrizePicks | 13.50 | 8.34 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Receiving - Receptions | 3.50 | 4.80 | Over |
| Buffalo vs. Washington | James Cook | Fantasy Points - PrizePicks | 11.50 | 7.26 | Under |
| New Orleans vs. Green Bay | Jordan Love | Offense - Passing - Interceptions | 0.50 | 0.32 | Under |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Fantasy Points - PrizePicks | 9.50 | 6.06 | Under |
| Chicago vs. Kansas City | D.J. Moore | Offense - Receiving - Yards | 44.50 | 60.60 | Over |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Fantasy Points - PrizePicks | 14.50 | 9.29 | Under |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Rushing - Yards | 71.50 | 96.80 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Rushing - Attempts | 12.50 | 16.89 | Over |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Rushing and Receiving Yards | 90.50 | 122.13 | Over |
| Denver vs. Miami | Samaje Perine | Offense - Rushing - Yards | 20.50 | 27.60 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Rushing - Attempts | 9.50 | 12.73 | Over |
| Houston vs. Jacksonville | Travis Etienne | Fantasy Points - PrizePicks | 14.50 | 9.61 | Under |
| Dallas vs. Arizona | Zach Ertz | Offense - Receiving - Yards | 30.50 | 40.67 | Over |
| New Orleans vs. Green Bay | Anders Carlson | Special Teams - Field Goals Made | 1.50 | 1.00 | Under |
| Dallas vs. Arizona | Brandon Aubrey | Special Teams - Field Goals Made | 1.50 | 2.00 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Rushing - Yards | 4.50 | 3.00 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Rushing - Yards | 12.50 | 16.64 | Over |
| Chicago vs. Kansas City | Cole Kmet | Fantasy Points - PrizePicks | 7.50 | 9.96 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Fantasy Points - PrizePicks | 10.50 | 13.89 | Over |
| Houston vs. Jacksonville | Dameon Pierce | Offense - Rushing and Receiving Yards | 60.50 | 79.67 | Over |
| New England vs. NY Jets | Garrett Wilson | Offense - Receiving - Receptions | 4.00 | 5.26 | Over |
| Atlanta vs. Detroit | Mack Hollins | Offense - Receiving - Receptions | 2.50 | 3.29 | Over |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Rushing - Attempts | 17.50 | 22.95 | Over |
| New England vs. NY Jets | Hunter Henry | Offense - Receiving - Yards | 29.50 | 38.64 | Over |
| Dallas vs. Arizona | James Conner | Offense - Rushing - Yards | 54.50 | 70.90 | Over |
| New Orleans vs. Green Bay | Chris Olave | Fantasy Points - PrizePicks | 14.00 | 9.82 | Under |
| Indianapolis vs. Baltimore | Alec Pierce | Offense - Receiving - Yards | 32.50 | 22.80 | Under |
| Denver vs. Miami | Raheem Mostert | Fantasy Points - PrizePicks | 13.50 | 9.48 | Under |
| Denver vs. Miami | Javonte Williams | Offense - Receiving - Yards | 14.50 | 10.20 | Under |
| Buffalo vs. Washington | James Cook | Offense - Rushing and Receiving Yards | 74.50 | 52.99 | Under |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Rushing and Receiving Yards | 89.50 | 115.25 | Over |
| New England vs. NY Jets | DeVante Parker | Fantasy Points - PrizePicks | 8.50 | 6.08 | Under |
| Dallas vs. Arizona | Zach Ertz | Offense - Receiving - Receptions | 4.00 | 5.14 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Rushing and Receiving Yards | 64.50 | 82.77 | Over |
| Philadelphia vs. Tampa Bay | Rachaad White | Fantasy Points - PrizePicks | 13.00 | 9.32 | Under |
| Atlanta vs. Detroit | Desmond Ridder | Fantasy Points - PrizePicks | 14.00 | 10.08 | Under |
| Carolina vs. Seattle | Adam Thielen | Fantasy Points - PrizePicks | 8.50 | 6.12 | Under |
| LA Chargers vs. Minnesota | T.J. Hockenson | Fantasy Points - PrizePicks | 13.50 | 9.72 | Under |
| Denver vs. Miami | Samaje Perine | Offense - Rushing and Receiving Yards | 41.50 | 30.00 | Under |
| Buffalo vs. Washington | Terry McLaurin | Offense - Receiving - Yards | 51.50 | 65.50 | Over |
| LA Chargers vs. Minnesota | Cameron Dicker | Special Teams - Field Goals Made | 1.50 | 1.90 | Over |
| Atlanta vs. Detroit | Riley Patterson | Special Teams - Field Goals Made | 1.50 | 1.90 | Over |
| Atlanta vs. Detroit | Younghoe Koo | Special Teams - Field Goals Made | 1.50 | 1.90 | Over |
| Carolina vs. Seattle | Jason Myers | Special Teams - Field Goals Made | 1.50 | 1.90 | Over |
| Tennessee vs. Cleveland | Myles Garrett | Defense - Sacks | 0.75 | 0.95 | Over |
| LA Chargers vs. Minnesota | Justin Jefferson | Fantasy Points - PrizePicks | 21.00 | 15.44 | Under |
| Houston vs. Jacksonville | Christian Kirk | Fantasy Points - PrizePicks | 12.50 | 9.22 | Under |
| Houston vs. Jacksonville | Nico Collins | Fantasy Points - PrizePicks | 12.00 | 8.90 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Rushing - Yards | 48.50 | 36.00 | Under |
| Houston vs. Jacksonville | Dalton Schultz | Offense - Receiving - Yards | 31.50 | 39.60 | Over |
| Denver vs. Miami | Courtland Sutton | Fantasy Points - PrizePicks | 10.00 | 7.43 | Under |
| Dallas vs. Arizona | Brandin Cooks | Offense - Receiving - Yards | 39.50 | 49.64 | Over |
| New England vs. NY Jets | Tyler Conklin | Offense - Receiving - Yards | 22.50 | 16.80 | Under |
| New England vs. NY Jets | Zach Wilson | Offense - Passing - Completions | 17.50 | 13.11 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing and Rushing Yards | 244.50 | 183.60 | Under |
| Philadelphia vs. Tampa Bay | DeVonta Smith | Offense - Receiving - Yards | 61.50 | 76.68 | Over |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Rushing - Yards | 34.50 | 42.91 | Over |
| New England vs. NY Jets | Michael Carter | Offense - Rushing - Yards | 8.50 | 6.43 | Under |
| Dallas vs. Arizona | James Conner | Offense - Receiving - Yards | 16.50 | 20.49 | Over |
| Philadelphia vs. Tampa Bay | Mike Evans | Fantasy Points - PrizePicks | 12.50 | 9.48 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Rushing - Yards | 12.50 | 15.49 | Over |
| Philadelphia vs. Tampa Bay | Mike Evans | Offense - Receiving - Yards | 54.50 | 67.37 | Over |
| Dallas vs. Arizona | CeeDee Lamb | Offense - Receiving - Yards | 69.50 | 85.72 | Over |
| Dallas vs. Arizona | Tony Pollard | Offense - Rushing - Yards | 72.50 | 55.90 | Under |
| New England vs. NY Jets | Ezekiel Elliott | Offense - Receiving - Yards | 6.50 | 7.99 | Over |
| Carolina vs. Seattle | Hayden Hurst | Offense - Receiving - Yards | 30.50 | 37.48 | Over |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Yards | 230.50 | 177.76 | Under |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Fantasy Points - PrizePicks | 14.50 | 17.80 | Over |
| Buffalo vs. Washington | Jahan Dotson | Offense - Receiving - Receptions | 3.50 | 2.71 | Under |
| Houston vs. Jacksonville | Calvin Ridley | Fantasy Points - PrizePicks | 15.00 | 11.62 | Under |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Receiving - Receptions | 3.50 | 4.29 | Over |
| Chicago vs. Kansas City | Khalil Herbert | Fantasy Points - PrizePicks | 8.50 | 6.60 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing - Yards | 232.50 | 180.86 | Under |
| Buffalo vs. Washington | Josh Allen | Offense - Rushing - Yards | 30.50 | 37.20 | Over |
| Atlanta vs. Detroit | Drake London | Fantasy Points - PrizePicks | 11.00 | 8.59 | Under |
| LA Chargers vs. Minnesota | Mike Williams | Fantasy Points - PrizePicks | 14.00 | 10.98 | Under |
| Buffalo vs. Washington | James Cook | Offense - Rushing - Yards | 54.50 | 42.87 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Rushing - Yards | 15.50 | 18.80 | Over |
| New England vs. NY Jets | Tyler Conklin | Offense - Receiving - Receptions | 2.50 | 1.97 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Fantasy Points - PrizePicks | 11.50 | 9.09 | Under |
| Carolina vs. Seattle | Adam Thielen | Offense - Receiving - Yards | 37.50 | 29.70 | Under |
| Indianapolis vs. Baltimore | Lamar Jackson | Offense - Rushing - Attempts | 8.50 | 6.73 | Under |
| Dallas vs. Arizona | Marquise Brown | Fantasy Points - PrizePicks | 10.50 | 8.33 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Rushing - Yards | 60.50 | 73.00 | Over |
| Philadelphia vs. Tampa Bay | A.J. Brown | Offense - Receiving - Yards | 68.50 | 82.60 | Over |
| Dallas vs. Arizona | CeeDee Lamb | Offense - Rushing and Receiving Yards | 74.50 | 89.82 | Over |
| Pittsburgh vs. Las Vegas | T.J. Watt | Defense - Sacks | 0.75 | 0.60 | Under |
| Houston vs. Jacksonville | Brandon McManus | Special Teams - Field Goals Made | 1.50 | 1.20 | Under |
| Houston vs. Jacksonville | Travis Etienne | Offense - Receiving - Receptions | 2.50 | 2.00 | Under |
| Chicago vs. Kansas City | Marquez Valdes-Scantling | Offense - Receiving - Yards | 27.50 | 33.00 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Rushing - Yards | 4.50 | 3.60 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Interceptions | 0.50 | 0.60 | Under |
| Atlanta vs. Detroit | Desmond Ridder | Offense - Rushing - Yards | 13.50 | 10.80 | Under |
| LA Rams vs. Cincinnati | Matthew Stafford | Offense - Passing - Interceptions | 0.50 | 0.60 | Under |
| Tennessee vs. Cleveland | Dustin Hopkins | Special Teams - Field Goals Made | 1.50 | 1.80 | Over |
| Philadelphia vs. Tampa Bay | Jake Elliott | Special Teams - Field Goals Made | 1.50 | 1.80 | Over |
| Buffalo vs. Washington | Tyler Bass | Special Teams - Field Goals Made | 1.50 | 1.80 | Over |
| Tennessee vs. Cleveland | Nick Folk | Special Teams - Field Goals Made | 1.50 | 1.80 | Over |
| LA Chargers vs. Minnesota | Keenan Allen | Offense - Receiving - Yards | 68.50 | 82.20 | Over |
| Pittsburgh vs. Las Vegas | George Pickens | Fantasy Points - PrizePicks | 11.50 | 9.21 | Under |
| Pittsburgh vs. Las Vegas | Davante Adams | Fantasy Points - PrizePicks | 15.50 | 12.42 | Under |
| Dallas vs. Arizona | James Conner | Offense - Rushing and Receiving Yards | 76.50 | 91.58 | Over |
| Pittsburgh vs. Las Vegas | George Pickens | Offense - Receiving - Receptions | 4.00 | 3.22 | Under |
| New England vs. NY Jets | Hunter Henry | Fantasy Points - PrizePicks | 8.50 | 6.87 | Under |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Rushing - Yards | 13.50 | 16.08 | Over |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing and Rushing Yards | 262.50 | 212.57 | Under |
| LA Chargers vs. Minnesota | Gerald Everett | Offense - Receiving - Yards | 32.50 | 26.40 | Under |
| Philadelphia vs. Tampa Bay | Dallas Goedert | Offense - Receiving - Yards | 38.50 | 45.69 | Over |
| Denver vs. Miami | Raheem Mostert | Offense - Rushing - Yards | 60.50 | 49.20 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Rushing - Yards | 57.50 | 46.80 | Under |
| Houston vs. Jacksonville | Evan Engram | Offense - Receiving - Yards | 40.50 | 48.00 | Over |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Receiving - Yards | 17.50 | 20.74 | Over |
| Buffalo vs. Washington | Sam Howell | Offense - Passing - Yards | 223.50 | 183.74 | Under |
| New Orleans vs. Green Bay | Rashid Shaheed | Offense - Receiving - Yards | 40.50 | 47.53 | Over |
| Pittsburgh vs. Las Vegas | Pat Freiermuth | Fantasy Points - PrizePicks | 8.50 | 7.03 | Under |
| Philadelphia vs. Tampa Bay | DeVonta Smith | Offense - Receiving - Receptions | 5.00 | 5.85 | Over |
| New England vs. NY Jets | Rhamondre Stevenson | Fantasy Points - PrizePicks | 14.50 | 12.04 | Under |
| Dallas vs. Arizona | Tony Pollard | Fantasy Points - PrizePicks | 17.00 | 14.16 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Touchdowns | 1.50 | 1.75 | Over |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing - Yards | 224.50 | 187.27 | Under |
| New England vs. NY Jets | DeVante Parker | Offense - Receiving - Yards | 34.50 | 28.80 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Attempts | 34.50 | 28.84 | Under |
| Denver vs. Miami | Samaje Perine | Offense - Receiving - Yards | 16.50 | 13.80 | Under |
| LA Chargers vs. Minnesota | K.J. Osborn | Offense - Receiving - Yards | 36.50 | 30.60 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Fantasy Points - PrizePicks | 15.00 | 12.58 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Rushing - Yards | 16.50 | 19.11 | Over |
| Indianapolis vs. Baltimore | Mark Andrews | Offense - Receiving - Receptions | 4.50 | 3.80 | Under |
| Pittsburgh vs. Las Vegas | Pat Freiermuth | Offense - Receiving - Yards | 32.50 | 37.57 | Over |
| Atlanta vs. Detroit | Desmond Ridder | Offense - Passing - Yards | 195.50 | 165.00 | Under |
| New England vs. NY Jets | Zach Wilson | Offense - Passing - Attempts | 29.50 | 24.90 | Under |
| Buffalo vs. Washington | Stefon Diggs | Fantasy Points - PrizePicks | 15.50 | 13.09 | Under |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Rushing - Yards | 72.50 | 83.70 | Over |
| Tennessee vs. Cleveland | Derrick Henry | Offense - Rushing - Attempts | 16.50 | 19.05 | Over |
| Pittsburgh vs. Las Vegas | Davante Adams | Offense - Receiving - Yards | 76.50 | 88.20 | Over |
| Denver vs. Miami | Courtland Sutton | Offense - Receiving - Receptions | 3.50 | 4.04 | Over |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Receiving - Yards | 8.50 | 7.21 | Under |
| Denver vs. Miami | Raheem Mostert | Offense - Rushing and Receiving Yards | 78.50 | 66.60 | Under |
| Atlanta vs. Detroit | Amon-Ra St. Brown | Offense - Rushing and Receiving Yards | 75.50 | 86.82 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Touchdowns | 1.50 | 1.72 | Over |
| Dallas vs. Arizona | Dak Prescott | Fantasy Points - PrizePicks | 16.50 | 18.94 | Over |
| Atlanta vs. Detroit | Amon-Ra St. Brown | Offense - Receiving - Yards | 73.50 | 84.12 | Over |
| Indianapolis vs. Baltimore | Michael Pittman | Offense - Receiving - Yards | 58.50 | 50.05 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Passing - Completions | 22.50 | 19.27 | Under |
| LA Rams vs. Cincinnati | Tyler Higbee | Offense - Receiving - Yards | 31.50 | 36.00 | Over |
| Indianapolis vs. Baltimore | Kylen Granson | Offense - Receiving - Yards | 24.50 | 21.00 | Under |
| Buffalo vs. Washington | Sam Howell | Offense - Passing and Rushing Yards | 241.50 | 207.07 | Under |
| Dallas vs. Arizona | Marquise Brown | Offense - Receiving - Yards | 41.50 | 47.41 | Over |
| Denver vs. Miami | Javonte Williams | Fantasy Points - PrizePicks | 11.50 | 9.88 | Under |
| Buffalo vs. Washington | Gabriel Davis | Offense - Receiving - Yards | 40.50 | 46.20 | Over |
| New Orleans vs. Green Bay | Juwan Johnson | Offense - Receiving - Yards | 29.50 | 33.65 | Over |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Rushing - Yards | 26.50 | 30.23 | Over |
| Denver vs. Miami | Jerry Jeudy | Fantasy Points - PrizePicks | 11.50 | 13.11 | Over |
| Indianapolis vs. Baltimore | Mark Andrews | Offense - Receiving - Yards | 53.50 | 46.02 | Under |
| Philadelphia vs. Tampa Bay | Baker Mayfield | Offense - Passing - Completions | 21.50 | 18.50 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Rushing - Attempts | 2.50 | 2.85 | Over |
| Carolina vs. Seattle | Andy Dalton | Fantasy Points - PrizePicks | 13.00 | 11.20 | Under |
| Indianapolis vs. Baltimore | Rashod Bateman | Offense - Receiving - Yards | 36.50 | 41.50 | Over |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Rushing - Attempts | 9.50 | 10.80 | Over |
| Denver vs. Miami | Tyreek Hill | Offense - Receiving - Receptions | 6.50 | 5.62 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing and Rushing Yards | 237.50 | 205.54 | Under |
| Pittsburgh vs. Las Vegas | Daniel Carlson | Special Teams - Field Goals Made | 1.50 | 1.70 | Over |
| Buffalo vs. Washington | Gabriel Davis | Offense - Receiving - Receptions | 3.00 | 3.40 | Under |
| Chicago vs. Kansas City | Harrison Butker | Special Teams - Field Goals Made | 1.50 | 1.70 | Over |
| Houston vs. Jacksonville | Robert Woods | Offense - Receiving - Yards | 37.50 | 32.52 | Under |
| Carolina vs. Seattle | Miles Sanders | Fantasy Points - PrizePicks | 13.00 | 11.28 | Under |
| Philadelphia vs. Tampa Bay | Cade Otton | Offense - Receiving - Yards | 26.50 | 23.01 | Under |
| Denver vs. Miami | Adam Trautman | Offense - Receiving - Yards | 18.50 | 16.09 | Under |
| Philadelphia vs. Tampa Bay | Dallas Goedert | Fantasy Points - PrizePicks | 9.50 | 8.26 | Under |
| Tennessee vs. Cleveland | David Njoku | Fantasy Points - PrizePicks | 8.00 | 6.96 | Under |
| Dallas vs. Arizona | Tony Pollard | Offense - Rushing and Receiving Yards | 95.50 | 83.12 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing - Completions | 25.50 | 28.77 | Over |
| Chicago vs. Kansas City | Noah Gray | Offense - Receiving - Yards | 16.50 | 18.60 | Over |
| Denver vs. Miami | Tyreek Hill | Fantasy Points - PrizePicks | 18.00 | 15.71 | Under |
| Chicago vs. Kansas City | Travis Kelce | Fantasy Points - PrizePicks | 16.50 | 14.41 | Under |
| Denver vs. Miami | Russell Wilson | Fantasy Points - PrizePicks | 15.50 | 17.46 | Over |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Completions | 21.50 | 24.21 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing - Touchdowns | 1.50 | 1.69 | Over |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Attempts | 32.50 | 36.59 | Over |
| Denver vs. Miami | Tua Tagovailoa | Offense - Rushing - Attempts | 2.50 | 2.19 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Rushing - Attempts | 3.50 | 3.07 | Under |
| Pittsburgh vs. Las Vegas | Allen Robinson | Fantasy Points - PrizePicks | 8.50 | 7.46 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Passing - Yards | 264.50 | 296.90 | Over |
| Buffalo vs. Washington | Sam Howell | Fantasy Points - PrizePicks | 15.00 | 16.83 | Over |
| Tennessee vs. Cleveland | David Njoku | Offense - Receiving - Yards | 30.50 | 34.20 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Fantasy Points - PrizePicks | 14.50 | 16.24 | Over |
| Houston vs. Jacksonville | Christian Kirk | Offense - Receiving - Receptions | 5.00 | 4.40 | Under |
| Atlanta vs. Detroit | Marvin Jones | Offense - Receiving - Yards | 22.50 | 25.19 | Over |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing - Completions | 19.50 | 17.18 | Under |
| Buffalo vs. Washington | Josh Allen | Fantasy Points - PrizePicks | 20.50 | 22.92 | Over |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Yards | 236.50 | 208.60 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Rushing - Attempts | 14.50 | 16.20 | Over |
| Indianapolis vs. Baltimore | Gus Edwards | Offense - Rushing - Yards | 48.50 | 42.80 | Under |
| New England vs. NY Jets | Mac Jones | Fantasy Points - PrizePicks | 13.50 | 15.08 | Over |
| Tennessee vs. Cleveland | Amari Cooper | Offense - Receiving - Yards | 58.50 | 65.27 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Interceptions | 0.50 | 0.55 | Under |
| New England vs. NY Jets | Mike Gesicki | Offense - Receiving - Yards | 20.50 | 18.26 | Under |
| LA Chargers vs. Minnesota | T.J. Hockenson | Offense - Receiving - Yards | 52.50 | 46.80 | Under |
| LA Chargers vs. Minnesota | Keenan Allen | Offense - Receiving - Receptions | 6.50 | 7.20 | Over |
| Houston vs. Jacksonville | Calvin Ridley | Offense - Receiving - Receptions | 5.50 | 6.08 | Over |
| Denver vs. Miami | Samaje Perine | Offense - Receiving - Receptions | 2.50 | 2.76 | Over |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing - Completions | 20.50 | 18.35 | Under |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Rushing - Attempts | 8.50 | 7.61 | Under |
| Carolina vs. Seattle | Andy Dalton | Offense - Passing - Yards | 213.50 | 191.38 | Under |
| Houston vs. Jacksonville | Calvin Ridley | Offense - Receiving - Yards | 69.50 | 62.36 | Under |
| Atlanta vs. Detroit | Amon-Ra St. Brown | Fantasy Points - PrizePicks | 15.50 | 13.92 | Under |
| Carolina vs. Seattle | Kenneth Walker III | Fantasy Points - PrizePicks | 13.50 | 12.12 | Under |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing - Attempts | 27.50 | 24.70 | Under |
| New England vs. NY Jets | Mac Jones | Offense - Passing - Yards | 211.50 | 233.00 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing - Yards | 177.50 | 159.58 | Under |
| Dallas vs. Arizona | CeeDee Lamb | Offense - Receiving - Receptions | 6.00 | 6.60 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Attempts | 30.50 | 33.55 | Over |
| Indianapolis vs. Baltimore | Michael Pittman | Fantasy Points - PrizePicks | 12.50 | 11.26 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Attempts | 29.50 | 26.62 | Under |
| Dallas vs. Arizona | James Conner | Offense - Rushing - Attempts | 14.50 | 15.91 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Rushing and Receiving Yards | 48.50 | 43.80 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Rushing - Attempts | 3.50 | 3.84 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Rushing - Yards | 9.50 | 8.59 | Under |
| Chicago vs. Kansas City | Travis Kelce | Offense - Receiving - Receptions | 6.50 | 5.89 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Receiving - Yards | 22.50 | 20.40 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Completions | 21.00 | 22.89 | Over |
| Pittsburgh vs. Las Vegas | Allen Robinson | Offense - Receiving - Receptions | 3.50 | 3.81 | Over |
| Atlanta vs. Detroit | Mack Hollins | Offense - Receiving - Yards | 30.50 | 33.19 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Receiving - Receptions | 2.50 | 2.72 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Rushing - Yards | 64.50 | 70.04 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Receiving - Yards | 10.50 | 11.40 | Over |
| Pittsburgh vs. Las Vegas | Najee Harris | Offense - Receiving - Yards | 10.50 | 9.60 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing and Rushing Yards | 287.50 | 263.23 | Under |
| Carolina vs. Seattle | Tyler Lockett | Fantasy Points - PrizePicks | 12.50 | 11.45 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing - Completions | 25.50 | 23.36 | Under |
| Dallas vs. Arizona | James Conner | Fantasy Points - PrizePicks | 13.00 | 14.09 | Over |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Rushing - Attempts | 13.50 | 12.37 | Under |
| New England vs. NY Jets | Rhamondre Stevenson | Offense - Rushing and Receiving Yards | 85.50 | 78.40 | Under |
| Denver vs. Miami | Javonte Williams | Offense - Rushing and Receiving Yards | 67.50 | 62.04 | Under |
| Houston vs. Jacksonville | Trevor Lawrence | Fantasy Points - PrizePicks | 17.50 | 18.91 | Over |
| Carolina vs. Seattle | Tyler Lockett | Offense - Receiving - Receptions | 4.50 | 4.86 | Over |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Completions | 21.50 | 23.22 | Over |
| Pittsburgh vs. Las Vegas | Jakobi Meyers | Offense - Receiving - Yards | 49.50 | 53.46 | Over |
| Indianapolis vs. Baltimore | Michael Pittman | Offense - Receiving - Receptions | 5.50 | 5.93 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Fantasy Points - PrizePicks | 13.00 | 11.99 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing - Attempts | 37.50 | 40.38 | Over |
| Dallas vs. Arizona | Zach Ertz | Fantasy Points - PrizePicks | 9.00 | 8.33 | Under |
| Dallas vs. Arizona | Tony Pollard | Offense - Receiving - Yards | 17.50 | 16.20 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Fantasy Points - PrizePicks | 24.00 | 22.25 | Under |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Rushing and Receiving Yards | 70.50 | 65.37 | Under |
| Philadelphia vs. Tampa Bay | Chris Godwin | Fantasy Points - PrizePicks | 13.00 | 12.07 | Under |
| LA Chargers vs. Minnesota | Mike Williams | Offense - Receiving - Yards | 64.50 | 69.08 | Over |
| Pittsburgh vs. Las Vegas | Allen Robinson | Offense - Receiving - Yards | 35.50 | 38.01 | Over |
| LA Chargers vs. Minnesota | Justin Jefferson | Offense - Rushing and Receiving Yards | 102.50 | 95.46 | Under |
| LA Chargers vs. Minnesota | Justin Jefferson | Offense - Receiving - Yards | 101.50 | 94.57 | Under |
| Buffalo vs. Washington | Stefon Diggs | Offense - Receiving - Receptions | 6.00 | 5.59 | Under |
| New England vs. NY Jets | Garrett Wilson | Fantasy Points - PrizePicks | 11.50 | 10.73 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing - Attempts | 38.50 | 35.92 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Rushing - Yards | 13.50 | 14.40 | Over |
| Tennessee vs. Cleveland | Amari Cooper | Offense - Receiving - Receptions | 4.50 | 4.20 | Under |
| New Orleans vs. Green Bay | Michael Thomas | Fantasy Points - PrizePicks | 12.00 | 12.80 | Over |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Yards | 194.50 | 207.29 | Over |
| Houston vs. Jacksonville | Travis Etienne | Offense - Rushing and Receiving Yards | 88.50 | 82.69 | Under |
| New Orleans vs. Green Bay | Chris Olave | Offense - Receiving - Receptions | 5.00 | 4.68 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Fantasy Points - PrizePicks | 23.00 | 24.46 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Rushing and Receiving Yards | 79.50 | 84.50 | Over |
| Dallas vs. Arizona | Marquise Brown | Offense - Receiving - Receptions | 4.00 | 4.25 | Under |
| Chicago vs. Kansas City | Khalil Herbert | Offense - Rushing and Receiving Yards | 46.50 | 49.36 | Over |
| Houston vs. Jacksonville | Robert Woods | Offense - Receiving - Receptions | 3.50 | 3.72 | Over |
| Carolina vs. Seattle | Kenneth Walker III | Offense - Rushing - Attempts | 15.50 | 16.42 | Over |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Rushing - Yards | 8.50 | 9.00 | Over |
| Denver vs. Miami | Tua Tagovailoa | Fantasy Points - PrizePicks | 17.50 | 18.53 | Over |
| Tennessee vs. Cleveland | Derrick Henry | Fantasy Points - PrizePicks | 15.00 | 15.87 | Over |
| Atlanta vs. Detroit | Jared Goff | Fantasy Points - PrizePicks | 17.50 | 18.49 | Over |
| Houston vs. Jacksonville | Travis Etienne | Offense - Rushing - Attempts | 15.50 | 14.63 | Under |
| Denver vs. Miami | Courtland Sutton | Offense - Receiving - Yards | 46.50 | 43.90 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing and Rushing Yards | 307.50 | 290.72 | Under |
| New England vs. NY Jets | Mac Jones | Offense - Passing and Rushing Yards | 224.50 | 236.73 | Over |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Completions | 20.50 | 21.62 | Over |
| Carolina vs. Seattle | Noah Fant | Offense - Receiving - Yards | 22.50 | 21.28 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Attempts | 32.50 | 34.24 | Over |
| Houston vs. Jacksonville | Travis Etienne | Offense - Rushing - Yards | 69.50 | 65.80 | Under |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing and Rushing Yards | 244.50 | 231.73 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing - Completions | 17.50 | 16.60 | Under |
| Pittsburgh vs. Las Vegas | Jakobi Meyers | Fantasy Points - PrizePicks | 10.50 | 11.04 | Over |
| Indianapolis vs. Baltimore | Kylen Granson | Offense - Receiving - Receptions | 2.50 | 2.63 | Under |
| LA Chargers vs. Minnesota | Keenan Allen | Fantasy Points - PrizePicks | 16.00 | 15.19 | Under |
| Buffalo vs. Washington | Terry McLaurin | Fantasy Points - PrizePicks | 10.50 | 9.98 | Under |
| Philadelphia vs. Tampa Bay | A.J. Brown | Fantasy Points - PrizePicks | 14.50 | 13.81 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing and Rushing Yards | 298.50 | 284.71 | Under |
| New Orleans vs. Green Bay | Michael Thomas | Offense - Receiving - Receptions | 5.00 | 5.23 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Fantasy Points - PrizePicks | 17.50 | 16.70 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Fantasy Points - PrizePicks | 20.00 | 19.09 | Under |
| Chicago vs. Kansas City | Travis Kelce | Offense - Receiving - Yards | 73.50 | 76.80 | Over |
| LA Chargers vs. Minnesota | Kirk Cousins | Fantasy Points - PrizePicks | 20.00 | 19.11 | Under |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Yards | 250.50 | 239.40 | Under |
| Philadelphia vs. Tampa Bay | Rachaad White | Offense - Rushing - Yards | 47.50 | 45.44 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Rushing - Attempts | 3.50 | 3.65 | Under |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing and Rushing Yards | 243.50 | 233.35 | Under |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing - Yards | 284.50 | 272.80 | Under |
| New Orleans vs. Green Bay | Michael Thomas | Offense - Receiving - Yards | 55.50 | 57.76 | Over |
| LA Chargers vs. Minnesota | Justin Jefferson | Offense - Receiving - Receptions | 7.50 | 7.19 | Under |
| LA Rams vs. Cincinnati | Matthew Stafford | Offense - Passing - Yards | 252.50 | 242.38 | Under |
| LA Chargers vs. Minnesota | Mike Williams | Offense - Receiving - Receptions | 5.00 | 4.80 | Under |
| Pittsburgh vs. Las Vegas | Josh Jacobs | Offense - Receiving - Receptions | 2.50 | 2.40 | Under |
| Philadelphia vs. Tampa Bay | A.J. Brown | Offense - Receiving - Receptions | 5.00 | 4.80 | Under |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing - Yards | 237.50 | 228.26 | Under |
| Tennessee vs. Cleveland | Ryan Tannehill | Offense - Passing and Rushing Yards | 208.50 | 216.58 | Over |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing - Yards | 292.50 | 281.20 | Under |
| Houston vs. Jacksonville | Travis Etienne | Offense - Receiving - Yards | 16.50 | 15.87 | Under |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing and Rushing Yards | 242.50 | 251.70 | Over |
| Chicago vs. Kansas City | Justin Fields | Offense - Passing - Completions | 16.50 | 15.88 | Under |
| Denver vs. Miami | Tua Tagovailoa | Offense - Passing - Attempts | 33.50 | 32.27 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing - Completions | 19.50 | 20.20 | Over |
| Chicago vs. Kansas City | D.J. Moore | Offense - Receiving - Receptions | 3.50 | 3.62 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Passing - Attempts | 30.50 | 29.43 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing - Attempts | 31.50 | 32.60 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Yards | 245.50 | 254.09 | Over |
| Pittsburgh vs. Las Vegas | George Pickens | Offense - Receiving - Yards | 50.50 | 48.83 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Passing - Attempts | 35.50 | 34.40 | Under |
| New England vs. NY Jets | Zach Wilson | Offense - Passing and Rushing Yards | 198.50 | 192.40 | Under |
| Atlanta vs. Detroit | Drake London | Offense - Receiving - Yards | 49.50 | 51.00 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Attempts | 33.50 | 34.51 | Over |
| Buffalo vs. Washington | Josh Allen | Offense - Passing - Completions | 21.50 | 20.92 | Under |
| Carolina vs. Seattle | Tyler Lockett | Offense - Receiving - Yards | 56.50 | 54.97 | Under |
| Pittsburgh vs. Las Vegas | Davante Adams | Offense - Receiving - Receptions | 6.00 | 5.84 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Attempts | 32.50 | 33.35 | Over |
| New England vs. NY Jets | Zach Wilson | Fantasy Points - PrizePicks | 10.50 | 10.23 | Under |
| LA Chargers vs. Minnesota | Kirk Cousins | Offense - Passing - Completions | 25.50 | 24.87 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing and Rushing Yards | 270.50 | 263.83 | Under |
| Houston vs. Jacksonville | Christian Kirk | Offense - Receiving - Yards | 54.50 | 55.81 | Over |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing - Yards | 235.50 | 229.89 | Under |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing and Rushing Yards | 264.50 | 270.74 | Over |
| Denver vs. Miami | Tyreek Hill | Offense - Receiving - Yards | 85.50 | 87.49 | Over |
| New England vs. NY Jets | Kendrick Bourne | Offense - Receiving - Yards | 30.50 | 31.20 | Over |
| New England vs. NY Jets | Zach Wilson | Offense - Passing - Yards | 180.50 | 176.40 | Under |
| New Orleans vs. Green Bay | Derek Carr | Fantasy Points - PrizePicks | 14.50 | 14.18 | Under |
| Buffalo vs. Washington | Josh Allen | Offense - Passing and Rushing Yards | 284.50 | 278.20 | Under |
| Carolina vs. Seattle | Geno Smith | Offense - Passing - Yards | 249.50 | 244.00 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Completions | 20.50 | 20.07 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing and Rushing Yards | 248.50 | 253.73 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Rushing - Yards | 28.50 | 29.09 | Over |
| New England vs. NY Jets | Zach Wilson | Offense - Rushing - Attempts | 3.50 | 3.43 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Passing and Rushing Yards | 250.50 | 245.53 | Under |
| Tennessee vs. Cleveland | Chigoziem Okonkwo | Offense - Receiving - Yards | 33.50 | 34.15 | Over |
| Carolina vs. Seattle | Geno Smith | Fantasy Points - PrizePicks | 17.50 | 17.16 | Under |
| New England vs. NY Jets | Breece Hall | Offense - Rushing - Attempts | 10.50 | 10.70 | Over |
| Buffalo vs. Washington | Jahan Dotson | Offense - Receiving - Yards | 44.50 | 43.70 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing and Rushing Yards | 197.50 | 194.00 | Under |
| Pittsburgh vs. Las Vegas | Pat Freiermuth | Offense - Receiving - Receptions | 3.50 | 3.44 | Under |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing - Completions | 20.50 | 20.16 | Under |
| Buffalo vs. Washington | Stefon Diggs | Offense - Receiving - Yards | 71.50 | 70.31 | Under |
| Houston vs. Jacksonville | Nico Collins | Offense - Receiving - Yards | 54.50 | 53.61 | Under |
| LA Rams vs. Cincinnati | Van Jefferson | Offense - Receiving - Yards | 37.50 | 38.11 | Over |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing and Rushing Yards | 295.50 | 290.69 | Under |
| Carolina vs. Seattle | Miles Sanders | Offense - Rushing and Receiving Yards | 80.50 | 79.20 | Under |
| Houston vs. Jacksonville | Dameon Pierce | Fantasy Points - PrizePicks | 10.50 | 10.33 | Under |
| LA Chargers vs. Minnesota | Donald Parham | Offense - Receiving - Yards | 17.50 | 17.78 | Over |
| Atlanta vs. Detroit | Kyle Pitts | Offense - Receiving - Yards | 33.50 | 33.00 | Under |
| Philadelphia vs. Tampa Bay | DeVonta Smith | Fantasy Points - PrizePicks | 14.50 | 14.29 | Under |
| Dallas vs. Arizona | Dak Prescott | Offense - Passing - Yards | 233.50 | 236.80 | Over |
| Pittsburgh vs. Las Vegas | Kenny Pickett | Offense - Passing - Attempts | 31.50 | 31.90 | Over |
| Denver vs. Miami | Russell Wilson | Offense - Passing - Yards | 230.50 | 227.66 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Passing - Yards | 267.50 | 264.57 | Under |
| LA Chargers vs. Minnesota | Justin Herbert | Offense - Passing - Yards | 283.50 | 280.40 | Under |
| Atlanta vs. Detroit | Jared Goff | Offense - Passing - Completions | 23.50 | 23.25 | Under |
| Houston vs. Jacksonville | Dameon Pierce | Offense - Receiving - Yards | 13.50 | 13.62 | Over |
| Houston vs. Jacksonville | Trevor Lawrence | Offense - Passing - Completions | 23.50 | 23.29 | Under |
| Chicago vs. Kansas City | Chase Claypool | Offense - Receiving - Yards | 22.50 | 22.69 | Over |
| Pittsburgh vs. Las Vegas | Jaylen Warren | Offense - Receiving - Yards | 15.50 | 15.60 | Over |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Passing - Attempts | 35.50 | 35.29 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Attempts | 30.50 | 30.67 | Over |
| New Orleans vs. Green Bay | Derek Carr | Offense - Passing - Attempts | 31.50 | 31.35 | Under |
| Dallas vs. Arizona | Joshua Dobbs | Offense - Passing - Yards | 180.50 | 179.67 | Under |
| New Orleans vs. Green Bay | Chris Olave | Offense - Receiving - Yards | 65.50 | 65.20 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Passing - Touchdowns | 1.50 | 1.51 | Under |
| Dallas vs. Arizona | CeeDee Lamb | Fantasy Points - PrizePicks | 16.00 | 15.94 | Under |
| Dallas vs. Arizona | Michael Gallup | Offense - Receiving - Yards | 25.50 | 25.59 | Over |
| Chicago vs. Kansas City | Patrick Mahomes | Offense - Rushing - Attempts | 3.50 | 3.51 | Under |
| Denver vs. Miami | Russell Wilson | Offense - Rushing - Attempts | 3.50 | 3.49 | Under |
| Philadelphia vs. Tampa Bay | Jalen Hurts | Offense - Rushing - Yards | 45.50 | 45.60 | Over |
| Pittsburgh vs. Las Vegas | Jimmy Garoppolo | Offense - Passing - Interceptions | 0.50 | 0.50 | Under |
| Tennessee vs. Cleveland | Deshaun Watson | Offense - Rushing - Attempts | 5.50 | 5.51 | Under |
| Chicago vs. Kansas City | D.J. Moore | Fantasy Points - PrizePicks | 10.50 | 10.49 | Under |
| Denver vs. Miami | Javonte Williams | Offense - Rushing - Yards | 49.50 | 49.52 | Over |
| Carolina vs. Seattle | Brian Burns | Defense - Sacks | 0.75 | 0.75 | Over |