Pick #1: 49ers -3 (-110)

First pick of the week as I have been busy last minute shopping. I really like the 49ers here even though AJ Brown is returning for the Titans. The 49ers are coming into fruition as Deebo Samuel is starting to be used is a rushing role. Jimmy G has also been playing as he is expected to be with his throwing being far improved from the beginning of the year. I think SF will outlast the Titans and straight up out score them. Hopefully winning by a touchdown or more.